<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-03-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000736952</issuerCik>
        <issuerName>TUXIS CORP</issuerName>
        <issuerTradingSymbol>TUX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001141394</rptOwnerCik>
            <rptOwnerName>INVESTOR SERVICE CENTER INC /DE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>11 HANOVER SQUARE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10005</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-03-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>8.79</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>200866</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Bassett S. Winmill may be deemed a controlling person of the Reporting Person. He owns in the aggregate 5,247 Issuer
shares in addition to, and which are not included in, the shares shown above. Mr. Winmill disclaims beneficial ownership of
such Issuer shares totalled above.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Thomas B. Winmill, General Counsel</signatureName>
        <signatureDate>2005-03-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
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X0202
4
2005-03-17
0
0000736952
TUXIS CORP
TUX
0001141394
INVESTOR SERVICE CENTER INC /DE
11 HANOVER SQUARE
NEW YORK
NY
10005
0
0
1
0
Common Stock
2005-03-17
4
P
0
1000
8.79
A
200866
D
Bassett S. Winmill may be deemed a controlling person of the Reporting Person. He owns in the aggregate 5,247 Issuer
shares in addition to, and which are not included in, the shares shown above. Mr. Winmill disclaims beneficial ownership of
such Issuer shares totalled above.
Thomas B. Winmill, General Counsel
2005-03-18