<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-04-04</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000725058</issuerCik>
        <issuerName>CYTOGEN CORP</issuerName>
        <issuerTradingSymbol>CYTO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001211252</rptOwnerCik>
            <rptOwnerName>BECKER MICHAEL D</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>650 COLLEGE ROAD EAST</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3100</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08540-5308</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2006-04-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>20000</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>59298</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Options to purchase Common Stock</value>
                <footnoteId id="F3"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.00</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2006-04-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>120000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2006-04-04</value>
            </exerciseDate>
            <expirationDate>
                <value>2016-04-04</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>120000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>120000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Such shares of restricted common stock were issued as a long-term incentive pursuant to the terms of the Company's 2004 Stock
 Incentive Plan and vest over a period of three years.</footnote>
        <footnote id="F2">34,000 of such shares of restricted common stock were issued as a long-term incentive pursuant to the terms of the Company's
 2004 Stock Incentive Plan and vest over a period of six years.</footnote>
        <footnote id="F3">Such options were granted pursuant to the terms of the Company's 2004 Stock Incentive Plan and vest in three equal annual
 installments beginning on the first anniversary of the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Michael D. Becker</signatureName>
        <signatureDate>2006-04-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
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X0202
4
2006-04-04
0
0000725058
CYTOGEN CORP
CYTO
0001211252
BECKER MICHAEL D
650 COLLEGE ROAD EAST
SUITE 3100
PRINCETON
NJ
08540-5308
0
1
0
0
President and CEO
Common Stock
2006-04-04
4
A
0
20000
0.00
A
59298
D
Options to purchase Common Stock
0.00
2006-04-04
4
A
0
120000
0
A
2006-04-04
2016-04-04
Common Stock
120000
120000
D
Such shares of restricted common stock were issued as a long-term incentive pursuant to the terms of the Company's 2004 Stock
 Incentive Plan and vest over a period of three years.
34,000 of such shares of restricted common stock were issued as a long-term incentive pursuant to the terms of the Company's
 2004 Stock Incentive Plan and vest over a period of six years.
Such options were granted pursuant to the terms of the Company's 2004 Stock Incentive Plan and vest in three equal annual
 installments beginning on the first anniversary of the date of grant.
/s/ Michael D. Becker
2006-04-06