<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-03-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000101778</issuerCik>
        <issuerName>MARATHON OIL CORP</issuerName>
        <issuerTradingSymbol>MRO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001549713</rptOwnerCik>
            <rptOwnerName>WAGNER PATRICK</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MARATHON OIL CORPORATION</rptOwnerStreet1>
            <rptOwnerStreet2>5555 SAN FELIPE ST.</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77056</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-03-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>66964</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>237292</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Restricted stock units granted under Marathon Oil Corporation's 2019 Incentive Compensation Plan, which vest in three equal, annual installments beginning one year from the date of grant.</footnote>
    </footnotes>

    <remarks>Executive Vice President, Corporate Development and Strategy</remarks>

    <ownerSignature>
        <signatureName>Anna Jones, Attorney-in-Fact for Patrick Wagner</signatureName>
        <signatureDate>2021-03-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
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X0306
4
2021-03-01
0
0000101778
MARATHON OIL CORP
MRO
0001549713
WAGNER PATRICK
C/O MARATHON OIL CORPORATION
5555 SAN FELIPE ST.
HOUSTON
TX
77056
0
1
0
0
See Remarks
Common Stock
2021-03-01
4
A
0
66964
0
A
237292
D
Restricted stock units granted under Marathon Oil Corporation's 2019 Incentive Compensation Plan, which vest in three equal, annual installments beginning one year from the date of grant.
Executive Vice President, Corporate Development and Strategy
Anna Jones, Attorney-in-Fact for Patrick Wagner
2021-03-03