content: <PAGE>   1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
  ================================================================================
                         SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
                             THE SECURITIES ACT OF 1933
  
                                    HEMASURE INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                                         04-3216862
  (State or other jurisdiction of                          (I.R.S. Employer
   incorporation or organization)                         Identification No.)
  
                  140 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
           (Address of Principal Executive Offices)       (Zip Code)
  
                              1994 DIRECTOR OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
  ================================================================================
                           CALCULATION OF REGISTRATION FEE
  <TABLE>
  <CAPTION>
                               Proposed    Proposed
  Title of                     maximum     maximum
  securities      Amount       offering    aggregate       Amount of
  to be           to be        price       offering        registration
  registered      registered   per share   price           fee
  - ----------      ----------   ---------   ---------       ---------------
  <S>             <C>          <C>         <C>             <C>
  Common Stock,   150,000      $15.75(1)   $2,362,500(1)   $815.00
  $.01 par        shares
  value
  </TABLE>
  
  - --------------------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  
  ================================================================================
  <PAGE>   2
  Statement of Incorporation by Reference
  - ---------------------------------------
           
       This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79722, relating
  to the Registrant's 1994 Director Option Plan.
  
  
  
                                        -2-
  <PAGE>   3
                                     SIGNATURES
  
            Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                          HEMASURE INC.
  
                                          By:/s/ Eugene J. Zurlo
                                             -----------------------
                                             Eugene J. Zurlo
                                             Chairman and
                                             Chief Executive Officer
  
                                
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of HemaSure Inc. hereby
  severally constitute Eugene J. Zurlo, James B. Murphy and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable HemaSure Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                         -3-
  <PAGE>   4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  
  Signature                     Title                             Date
                                -----                             ----
  
  /s/ Eugene J. Zurlo           Chief Executive              )
  - ----------------------        Officer and Chairman         )
  Eugene J. Zurlo               of the Board of              )
                                Directors (Principal         )
                                Executive Officer            )
                                                             )
  /s/ James B. Murphy           Senior Vice President        )
  - ----------------------        -- Finance and               )
  James B. Murphy               Administration (Principal    )
                                Financial and                )
                                Accounting Officer)          )
                                                             )
                                                             )
  /s/ Timothy J. Barberich      Director                     )
  - ------------------------                                   )
  Timothy J. Barberich                                       )
                                                             )
                                                             )
                                                             )
  /s/ David S. Barlow           Director                     )
  - ------------------------                                   )
  David S. Barlow                                            )
                                                             )  June 7, 1996
                                                             )
  /s/ John T. Kimbell           Director                     )
  - ------------------------                                   )
  John T. Kimbell                                            )
                                                             )
                                                             )
  /s/ Rolf S. Stutz             Director                     )
  - ------------------------                                   )
  Rolf S. Stutz                                              )
                                                             )
                                                             )
                                                             )
  
                                       -4-
  <PAGE>   5
                                    EXHIBIT INDEX
  <TABLE>
  <CAPTION>
  Exhibit
  Number                 Description                                              Page
  - -------                -----------                                              ----
  <S>                    <C>                                                       <C>
   4.1                   Certificate of Incorporation    
                         of the Registrant, as amended                             -
  
   4.2                   By-Laws of the Registrant                                 -
  
   4.3 *                 Specimen Certificate of Common Stock of
                         the Registrant                                            -                                     
  
   5                     Opinion of Hale and Dorr
  
  23.1                   Consent of Hale and Dorr (included in Exhibit 5)          -
  
  23.2                   Consent of Coopers & Lybrand L.L.P.
  
  24                     Power of Attorney (included in the signature pages
                         of this Registration Statement)                           -
  </TABLE>
  - --------------------------
  *        Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-1 (File No. 33-75930).
  
                                         -5-
metadata_documents: [{"type": "S-8", "sequence": "1", "description": "HEMASURE INC. 1994 DIRECTOR OPTION PLAN", "secsgml_size_bytes": 8569}]
metadata_filer: {"company-data": {"conformed-name": "HEMASURE INC", "cik": "0000919745", "assigned-sic": "3841", "irs-number": "043216862", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-05613", "film-number": "96578881"}, "business-address": {"street1": "140 LOCKE DR", "city": "MARLBOROUGH", "state": "MA", "zip": "01752", "phone": "5084856850"}, "mail-address": {"street1": "140 LOCKE DR", "city": "MARLOBOROUGH", "state": "MA", "zip": "01752"}, "former-company": {"former-conformed-name": "HEMEASURE INC", "date-changed": "19940303"}}
text: 1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
  ================================================================================
                         SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
                             THE SECURITIES ACT OF 1933
  
                                    HEMASURE INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                                         04-3216862
  (State or other jurisdiction of                          (I.R.S. Employer
   incorporation or organization)                         Identification No.)
  
                  140 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
           (Address of Principal Executive Offices)       (Zip Code)
  
                              1994 DIRECTOR OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
  ================================================================================
                           CALCULATION OF REGISTRATION FEE
  Proposed    Proposed
  Title of                     maximum     maximum
  securities      Amount       offering    aggregate       Amount of
  to be           to be        price       offering        registration
  registered      registered   per share   price           fee
  - ----------      ----------   ---------   ---------       ---------------
  Common Stock,   150,000      $15.75(1)   $2,362,500(1)   $815.00
  $.01 par        shares
  value
  - --------------------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  
  ================================================================================
  2
  Statement of Incorporation by Reference
  - ---------------------------------------
           
       This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79722, relating
  to the Registrant's 1994 Director Option Plan.
  
                                        -2-
  3
                                     SIGNATURES
  
            Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                          HEMASURE INC.
  
                                          By:/s/ Eugene J. Zurlo
                                             -----------------------
                                             Eugene J. Zurlo
                                             Chairman and
                                             Chief Executive Officer
  
                                
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of HemaSure Inc. hereby
  severally constitute Eugene J. Zurlo, James B. Murphy and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable HemaSure Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                         -3-
  4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  
  Signature                     Title                             Date
                                -----                             ----
  
  /s/ Eugene J. Zurlo           Chief Executive              )
  - ----------------------        Officer and Chairman         )
  Eugene J. Zurlo               of the Board of              )
                                Directors (Principal         )
                                Executive Officer            )
                                                             )
  /s/ James B. Murphy           Senior Vice President        )
  - ----------------------        -- Finance and               )
  James B. Murphy               Administration (Principal    )
                                Financial and                )
                                Accounting Officer)          )
                                                             )
                                                             )
  /s/ Timothy J. Barberich      Director                     )
  - ------------------------                                   )
  Timothy J. Barberich                                       )
                                                             )
                                                             )
                                                             )
  /s/ David S. Barlow           Director                     )
  - ------------------------                                   )
  David S. Barlow                                            )
                                                             )  June 7, 1996
                                                             )
  /s/ John T. Kimbell           Director                     )
  - ------------------------                                   )
  John T. Kimbell                                            )
                                                             )
                                                             )
  /s/ Rolf S. Stutz             Director                     )
  - ------------------------                                   )
  Rolf S. Stutz                                              )
                                                             )
                                                             )
                                                             )
  
                                       -4-
  5
                                    EXHIBIT INDEX
  Exhibit
  Number                 Description                                              Page
  - -------                -----------                                              ----
  4.1                   Certificate of Incorporation    
                         of the Registrant, as amended                             -
  
   4.2                   By-Laws of the Registrant                                 -
  
   4.3 *                 Specimen Certificate of Common Stock of
                         the Registrant                                            -                                     
  
   5                     Opinion of Hale and Dorr
  
  23.1                   Consent of Hale and Dorr (included in Exhibit 5)          -
  
  23.2                   Consent of Coopers & Lybrand L.L.P.
  
  24                     Power of Attorney (included in the signature pages
                         of this Registration Statement)                           -
  - --------------------------
  *        Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-1 (File No. 33-75930).
  
                                         -5-