content: <PAGE>   1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
  ================================================================================
  
                         SECURITIES AND EXCHANGE COMMISSION
  
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
  
                             THE SECURITIES ACT OF 1933
  
                                    HEMASURE INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                                              04-3216862
  (State or other jurisdiction of                               (I.R.S. Employer
   incorporation or organization)                              Identification No.)
  
                  140 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
                 (Address of Principal Executive Offices) (Zip Code)
  
                               1994 STOCK OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
  ================================================================================
  
                           CALCULATION OF REGISTRATION FEE
  
  <TABLE>
  <CAPTION>
                                 Proposed     Proposed
  Title of                       maximum      maximum
  securities       Amount        offering     aggregate       Amount of
  to be            to be         price        offering        registration
  registered       registered    per share    price           fee
  - ----------       ----------    ---------    ---------       ------------
  <S>              <C>           <C>         <C>              <C>      
  Common Stock,    1,500,000     $15.75(1)   $23,625,000(1)   $8,147.00
  $.01 par          shares                                   
  value                                                      
  </TABLE>
                                                             
  - --------------------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  
  ================================================================================
  <PAGE>   2
  Statement of Incorporation by Reference
  
           This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79720, relating
  to the Registrant's 1994 Stock Option Plan.
  
                                        -2-
  <PAGE>   3
                                     SIGNATURES
  
           Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                                       HEMASURE INC.
  
                                                       By: /s/ Eugene J. Zurlo
                                                           -------------------
                                                           Eugene J. Zurlo
                                                           Chairman and
                                                           Chief Executive Officer
  
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of HemaSure Inc. hereby
  severally constitute Eugene J. Zurlo, James B. Murphy and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable HemaSure Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                         -3-
  <PAGE>   4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  
  Signature                               Title                   Date
  - ---------                               -----                   ----
  
  /s/ Eugene J. Zurlo              Chief Executive                )
  - ----------------------------     Officer and Chairman           )
  Eugene J. Zurlo                  of the Board of                )
                                   Directors (Principal           )
                                   Executive Officer              )
                                                                  )
  /s/ James B. Murphy              Senior Vice President --       )
  - ----------------------------     Finance and Administration     )
  James B. Murphy                  (Principal Financial           )
                                   and Accounting Officer)        )
                                                                  )
  /s/ Timothy J. Barberich         Director                       )
  - ----------------------------                                    )
  Timothy J. Barberich                                            )
                                                                  )
                                                                  )
  /s/ David S. Barlow              Director                       )
  - ----------------------------                                    )
  David S. Barlow                                                 )
                                                                  ) June 7, 1996
                                                                  )
  /s/ John T. Kimbell              Director                       )
  - ----------------------------                                    )
  John T. Kimbell                                                 )
                                                                  )
                                                                  )
  /s/ Rolf S. Stutz                Director                       )
  - ----------------------------                                    )
  Rolf S. Stutz                                                   )
                                                                  )
  
                                        -4-
  <PAGE>   5
                                    EXHIBIT INDEX
  
  <TABLE>
  <CAPTION>
  Exhibit
  Number     Description                                                 Page
  - ------     -----------                                                 ----
  <S>        <C>                                                         <C>
   4.1 *     Certificate of Incorporation
             of the Registrant, as amended                                 -
  
   4.2 *     By-Laws of the Registrant                                     -
  
   4.3 **    Specimen Certificate of Common Stock of
             the Registrant                                                -
  
   5         Opinion of Hale and Dorr
  
  23.1       Consent of Hale and Dorr (included in Exhibit 5)              -
  
  23.2       Consent of Coopers & Lybrand L.L.P.
  
  24         Power of Attorney (included in the signature pages
             of this Registration Statement)                               -
  </TABLE>
  
  - -----------------
  *        Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-8 relating to the Registrants 1994 Director Option
           Plan filed on June 10, 1996.
  
  **       Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-1 (File No. 33-75930).
metadata_documents: [{"type": "S-8", "sequence": "1", "description": "HEMASURE, INC.", "secsgml_size_bytes": 8584}]
metadata_filer: {"company-data": {"conformed-name": "HEMASURE INC", "cik": "0000919745", "assigned-sic": "3841", "irs-number": "043216862", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-05615", "film-number": "96578885"}, "business-address": {"street1": "140 LOCKE DR", "city": "MARLBOROUGH", "state": "MA", "zip": "01752", "phone": "5084856850"}, "mail-address": {"street1": "140 LOCKE DR", "city": "MARLOBOROUGH", "state": "MA", "zip": "01752"}, "former-company": {"former-conformed-name": "HEMEASURE INC", "date-changed": "19940303"}}
text: 1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
  ================================================================================
  
                         SECURITIES AND EXCHANGE COMMISSION
  
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
  
                             THE SECURITIES ACT OF 1933
  
                                    HEMASURE INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                                              04-3216862
  (State or other jurisdiction of                               (I.R.S. Employer
   incorporation or organization)                              Identification No.)
  
                  140 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
                 (Address of Principal Executive Offices) (Zip Code)
  
                               1994 STOCK OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
  ================================================================================
  
                           CALCULATION OF REGISTRATION FEE
  Proposed     Proposed
  Title of                       maximum      maximum
  securities       Amount        offering     aggregate       Amount of
  to be            to be         price        offering        registration
  registered       registered    per share    price           fee
  - ----------       ----------    ---------    ---------       ------------
  Common Stock,    1,500,000     $15.75(1)   $23,625,000(1)   $8,147.00
  $.01 par          shares                                   
  value
  - --------------------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  
  ================================================================================
  2
  Statement of Incorporation by Reference
  
           This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79720, relating
  to the Registrant's 1994 Stock Option Plan.
  
                                        -2-
  3
                                     SIGNATURES
  
           Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                                       HEMASURE INC.
  
                                                       By: /s/ Eugene J. Zurlo
                                                           -------------------
                                                           Eugene J. Zurlo
                                                           Chairman and
                                                           Chief Executive Officer
  
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of HemaSure Inc. hereby
  severally constitute Eugene J. Zurlo, James B. Murphy and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable HemaSure Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                         -3-
  4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  
  Signature                               Title                   Date
  - ---------                               -----                   ----
  
  /s/ Eugene J. Zurlo              Chief Executive                )
  - ----------------------------     Officer and Chairman           )
  Eugene J. Zurlo                  of the Board of                )
                                   Directors (Principal           )
                                   Executive Officer              )
                                                                  )
  /s/ James B. Murphy              Senior Vice President --       )
  - ----------------------------     Finance and Administration     )
  James B. Murphy                  (Principal Financial           )
                                   and Accounting Officer)        )
                                                                  )
  /s/ Timothy J. Barberich         Director                       )
  - ----------------------------                                    )
  Timothy J. Barberich                                            )
                                                                  )
                                                                  )
  /s/ David S. Barlow              Director                       )
  - ----------------------------                                    )
  David S. Barlow                                                 )
                                                                  ) June 7, 1996
                                                                  )
  /s/ John T. Kimbell              Director                       )
  - ----------------------------                                    )
  John T. Kimbell                                                 )
                                                                  )
                                                                  )
  /s/ Rolf S. Stutz                Director                       )
  - ----------------------------                                    )
  Rolf S. Stutz                                                   )
                                                                  )
  
                                        -4-
  5
                                    EXHIBIT INDEX
  Exhibit
  Number     Description                                                 Page
  - ------     -----------                                                 ----
  4.1 *     Certificate of Incorporation
             of the Registrant, as amended                                 -
  
   4.2 *     By-Laws of the Registrant                                     -
  
   4.3 **    Specimen Certificate of Common Stock of
             the Registrant                                                -
  
   5         Opinion of Hale and Dorr
  
  23.1       Consent of Hale and Dorr (included in Exhibit 5)              -
  
  23.2       Consent of Coopers & Lybrand L.L.P.
  
  24         Power of Attorney (included in the signature pages
             of this Registration Statement)                               -
  - -----------------
  *        Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-8 relating to the Registrants 1994 Director Option
           Plan filed on June 10, 1996.
  
  **       Incorporated herein by reference from the Registrant's Registration
           Statement on Form S-1 (File No. 33-75930).