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  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>As
  filed with the Securities and Exchange Commission on July&nbsp;2, 2007</B>
  </DIV>
  
  
  <DIV align="right" style="font-size: 10pt; margin-top: 0pt"><B>Registration Statement No.&nbsp;333-</B>
  </DIV>
  
  
  <DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>
  <DIV style="width: 100%; border-bottom: 1pt solid black; font-size: 1pt">&nbsp;</DIV>
  
  
  
  
  <DIV align="center" style="font-size: 14pt; margin-top: 12pt"><B>UNITED STATES SECURITIES AND EXCHANGE COMMISSION</B>
  </DIV>
  
  <DIV align="center" style="font-size: 12pt"><B>WASHINGTON, D.C. 20549</B>
  </DIV>
  
  <DIV align="center" style="font-size: 18pt; margin-top: 12pt"><B>FORM S-8</B>
  </DIV>
  
  
  <DIV align="Center" style="font-size: 12pt; margin-top: 6pt"><B>REGISTRATION STATEMENT<BR>
  UNDER<BR>
  THE SECURITIES ACT OF 1933</B>
  
  </DIV>
  <DIV align="center" style="font-size: 24pt; margin-top: 12pt"><B>INVERNESS MEDICAL INNOVATIONS, INC.</B>
  </DIV>
  
  <DIV align="center" style="font-size: 10pt">(Exact Name of Registrant as Specified in Its Charter)</DIV>
  
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="30%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="30%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="30%">&nbsp;</TD>
  </TR>
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD align="center" valign="bottom"><B>Delaware</B>
  </TD>
      <TD>&nbsp;</TD>
      <TD align="center" valign="top"><B>51 Sawyer Road, Suite&nbsp;200<BR>
  Waltham, Massachusetts 02453<BR>
  (781)&nbsp;647-3900</B>
  </TD>
      <TD>&nbsp;</TD>
      <TD align="center" valign="bottom"><B>04-3565120</B></TD>
  </TR>
  <TR valign="bottom">
      <TD align="center" valign="top">(State of Incorporation)
  </TD>
      <TD>&nbsp;</TD>
      <TD align="center" valign="top">(Address of Registrant&#146;s
  Principal Executive
  Offices)
  </TD>
      <TD>&nbsp;</TD>
      <TD align="center" valign="top">(I.R.S. Employer<BR>
  Identification No.)</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan<BR>
  Biosite Incorporated 2002 Nonqualified Stock Incentive Plan</B><BR>
  (Full Title of the Plans)
  
  </DIV>
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Ron Zwanziger</B><BR>
  Chairman, Chief Executive Officer and President<BR>
  Inverness Medical Innovations, Inc.<BR>
  51 Sawyer Road, Suite&nbsp;200<BR>
  Waltham, Massachusetts 02453<BR>
  (781)&nbsp;647-3900<BR>
  (Name, address, including zip code, and telephone number, including area code, of agent for service)
  
  </DIV>
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>With copy to:</B>
  
  </DIV>
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Jay McNamara, Esq.</B><BR>
  Senior Counsel, Corporate &#038; Finance<BR>
  Inverness Medical Innovations, Inc.<BR>
  51 Sawyer Road, Suite&nbsp;200<BR>
  Waltham, Massachusetts 02453<BR>
  (781)&nbsp;647-3900
  
  </DIV>
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>CALCULATION OF REGISTRATION FEE</B>
  
  </DIV>
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="1%">&nbsp;</TD>
      <TD width="25%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="23%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="9%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="21%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="12%">&nbsp;</TD>
  
      <TD width="1%">&nbsp;</TD>
  </TR><TR style="font-size: 1px" valign="bottom">
      <TD nowrap align="left" colspan="15" style="border-bottom: 3px double #000000">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD>&nbsp;</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Proposed Maximum</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Proposed Maximum</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD nowrap align="center"><B>Title of Securities</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Amounts to be</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Offering Price</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Aggregate Offering</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Amount of</B></TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD nowrap align="center"><B>Being Registered</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Registered (1)</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Per Share(2)</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Price(2)</B></TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center"><B>Registration Fee(2)</B></TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
                      <TD style="border-top: 2px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock, par
  value $.001 per
  share</DIV></TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">1,051,317 shares(3)</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$25.73</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$27,050,386.41</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$830.45</TD>
      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock, par
  value $.001 per
  share</DIV></TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">1,060,253 shares(4)</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$28.16</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$29,856,724.48</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
  
  <TD align="center" valign="bottom" style="border-top: 2px solid #000000">$916.60</TD>
      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
  </TR>
  <TR style="font-size: 1px" valign="bottom">
      <TD nowrap align="left" colspan="15" style="border-top: 3px double #000000">&nbsp;</TD>
  </TR>
  
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="1%" nowrap align="left">(1)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>This registration statement also relates to such indeterminate number of additional shares of
  the registrant&#146;s Common Stock as may be required pursuant to the Biosite Incorporated Amended
  and Restated 1996 Stock Incentive Plan, and the Biosite Incorporated 2002 Nonqualified Stock
  Incentive Plan in the event of a stock dividend, stock split, split-up, recapitalization,
  forfeiture of stock under the plan or other similar event.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="1%" nowrap align="left">(2)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>This estimate is made pursuant to Rule 457(h)&nbsp;under the Securities Act of 1933, as
  amended, solely for the purposes of determining the amount of the
  registration fee. The aggregate offering price and the amount of the registration fee
  under each plan were calculated using the weighted average exercise
  price at which the options may be exercised.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="1%" nowrap align="left">(3)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>Represents shares of Inverness Medical Innovations, Inc. common stock issuable upon
  exercise of outstanding stock options granted pursuant to the Biosite Incorporated Amended and
  Restated 1996 Stock Incentive Plan.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="1%" nowrap align="left">(4)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>Represents shares of Inverness Medical Innovations, Inc. common stock issuable upon
  exercise of outstanding stock options granted pursuant to the Biosite Incorporated 2002
  Nonqualified Stock Incentive Plan.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="width: 100%; border-bottom: 1pt solid black; margin-top: 10pt; font-size: 1pt">&nbsp;</DIV>
  <DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>
  
  
  
  
  
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  
  
  <!-- TOC -->
  <A name="toc"><DIV align="CENTER" style="page-break-before:always"><U><B>TABLE OF CONTENTS</B></U></DIV></A>
  
  <P><CENTER>
  <TABLE border="0" width="90%" cellpadding="0" cellspacing="0">
  <TR>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="3%"></TD>
  	<TD width="76%"></TD>
  </TR>
  <TR><TD colspan="9"><A HREF="#000">PART I</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#001">ITEM 1. PLAN INFORMATION*</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#002">ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION*</A></TD></TR>
  <TR><TD colspan="9"><A HREF="#003">PART II</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#004">ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#005">ITEM 4. DESCRIPTION OF SECURITIES</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#006">ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#007">ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#008">ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#009">ITEM 8. EXHIBITS</A></TD></TR>
  <TR><TD></TD><TD colspan="8"><A HREF="#010">ITEM 9. UNDERTAKINGS</A></TD></TR>
  <TR><TD colspan="9"><A HREF="#011">SIGNATURES</A></TD></TR>
  <TR><TD colspan="9"><A HREF="#012">EXHIBIT INDEX</A></TD></TR>
  <TR><TD colspan="9"><A HREF="b65877s8exv4w6.htm">Ex-4.6 Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan</A></TD></TR>
  <TR><TD colspan="9"><A HREF="b65877s8exv4w7.htm">Ex-4.7 Biosite Incorporated 2002 Nonqualified Stock Incentive Plan</A></TD></TR>
  <TR><TD colspan="9"><A HREF="b65877s8exv5w1.htm">Ex-5.1 Opinion of Jay McNamara, Esq</A></TD></TR>
  <TR><TD colspan="9"><A HREF="b65877s8exv23w1.htm">Ex-23.1 Consent of BDO Seidman, LLP</A></TD></TR>
  <TR><TD colspan="9"><A HREF="b65877s8exv23w2.htm">Ex-23.2 Consent of Colby & Company, PLC</A></TD></TR>
  </TABLE>
  </CENTER>
  <!-- /TOC -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  
  
  
  
  
  
  <!-- link1 "PART I" -->
  <DIV align="left"><A NAME="000"></A></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART I<BR>
  INFORMATION REQUIRED IN THE 10(a) PROSPECTUS</B>
  </DIV>
  
  <!-- link2 "ITEM 1. PLAN INFORMATION*" -->
  <DIV align="left"><A NAME="001"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 1. PLAN INFORMATION.*</B>
  </DIV>
  
  <!-- link2 "ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION*" -->
  <DIV align="left"><A NAME="002"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.*</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">*Information required by Part&nbsp;I to be contained in the Section 10(a) prospectus is omitted from
  this registration statement in accordance with Rule&nbsp;428 under the Securities Act of 1933, as
  amended (the &#147;Securities Act&#148;), and the Introductory Note to Part&nbsp;I of Form S-8.
  </DIV>
  
  <!-- link1 "PART II" -->
  <DIV align="left"><A NAME="003"></A></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART II</B>
  </DIV>
  
  
  <DIV align="center" style="font-size: 10pt; margin-top: 0pt"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>
  </DIV>
  
  <!-- link2 "ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE" -->
  <DIV align="left"><A NAME="004"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">The following documents filed with the Securities and Exchange Commission (the &#147;Commission&#148;) are
  incorporated in this registration statement by reference:
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(a)&nbsp;the Company&#146;s Annual Report on Form 10-K for the fiscal year ended December&nbsp;31, 2006, filed
  with the Commission on March&nbsp;1, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(b)&nbsp;the Company&#146;s Amended Annual Report on Form 10-K/A for the fiscal year ended December&nbsp;31, 2006,
  filed with the Commission on March&nbsp;26, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(c)&nbsp;the Company&#146;s Quarterly Report on Form 10-Q for the quarter ended March&nbsp;31, 2007, filed with
  the Commission on May&nbsp;10, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(d)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on June&nbsp;12, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(e)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on June&nbsp;12, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(f)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on June&nbsp;4, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(g)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;29, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(h)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;23, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(i)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;18, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(j)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;15, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(k)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;15, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(l)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;11, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(m)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on May&nbsp;10, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(n)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on April&nbsp;30, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(o)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on April&nbsp;5, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(p)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on March&nbsp;16, 2007, as
  amended by the Company&#146;s Current Report on Form 8-K/A filed with the Commission on April&nbsp;23, 2007;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(q)&nbsp;the Company&#146;s Current Report on Form 8-K filed with the Commission on January&nbsp;26, 2007; and
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(r)&nbsp;the description of the Company&#146;s common stock contained in its Registration Statement on Form
  8-A filed with the Commission on November&nbsp;21, 2001, as amended, under Section&nbsp;12 of the Securities
  Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;) and any amendments or reports filed for the
  purpose of updating such description.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">In addition, all documents subsequently filed with the Commission by the Company pursuant to
  Sections&nbsp;13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
  amendment hereto which indicates that all securities offered have been sold or which deregisters
  all securities then remaining unsold, shall be deemed to be incorporated by reference in this
  registration statement and to be part hereof from the date of filing of such documents.
  </DIV>
  
  <!-- link2 "ITEM 4. DESCRIPTION OF SECURITIES" -->
  <DIV align="left"><A NAME="005"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 4. DESCRIPTION OF SECURITIES.</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Not applicable.
  </DIV>
  
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  
  <!-- link2 "ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL" -->
  <DIV align="left"><A NAME="006"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">The validity of the securities the Company is offering are being passed upon by Jay McNamara, Esq.,
  Senior Counsel, Corporate &#038; Finance, of the Company. Mr.&nbsp;McNamara owns an aggregate of
  approximately 2,529 shares of common stock of the Company, as well as options to purchase an
  additional 17,579 shares of common stock of the Company.
  </DIV>
  <!-- link2 "ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS" -->
  <DIV align="left"><A NAME="007"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Section&nbsp;145 of the Delaware General Corporation Law provides that a corporation may indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or
  completed action, suit or proceeding, whether civil, criminal, administrative or investigative,
  other than an action by or in the right of the corporation, by reason of the fact that the person
  is or was a director, officer, employee or agent of the corporation or is or was serving at the
  corporation&#146;s request as a director, officer, employee or agent of another corporation,
  partnership, joint venture, trust or other enterprise, against expenses, including attorneys&#146; fees,
  judgments, fines and amounts paid in settlement actually and reasonably incurred by the person in
  connection with the action, suit or proceeding if the person acted in good faith and in a manner
  the person reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe the
  person&#146;s conduct was unlawful. The power to indemnify applies to actions brought by or in the right
  of the corporation as well, but only to the extent of expenses, including attorneys&#146; fees but
  excluding judgments, fines and amounts paid in settlement, actually and reasonably incurred by the
  person in connection with the defense or settlement of the action or suit. And with the further
  limitation that in these actions, no indemnification shall be made in the event of any adjudication
  of negligence or misconduct in the performance of the person&#146;s duties to the corporation, unless a
  court believes that in light of all the circumstances indemnification should apply.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Article&nbsp;V of the Company&#146;s by-laws provides that the Company shall, to the extent legally
  permitted, indemnify each person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action, suit or proceeding by reason of the fact that such person
  is or was, or has agreed to become, a director or officer of the Company, or is or was serving, or
  has agreed to serve, at the request of the Company, as a director, officer, trustee, partner,
  employee or agent of, or in a similar capacity with, another corporation, partnership, joint
  venture, trust, employee benefit plan or other enterprise. The indemnification provided for in
  Article&nbsp;V is expressly not exclusive of any other rights to which those seeking indemnification may
  be entitled under any law, agreement or vote of stockholders or disinterested directors or
  otherwise, and shall inure to the benefit of the heirs, executors and administrators of such
  persons.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Section&nbsp;145(g) of the Delaware General Corporation Law and Article&nbsp;V of the by-laws of the Company
  provide that the Company shall have the power to purchase and maintain insurance on behalf of its
  officers, directors, employees and agents, against any liability asserted against and incurred by
  such persons in any such capacity.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">The Company has obtained insurance covering its directors and officers against losses and insuring
  the Company against certain of its obligations to indemnify its directors and officers.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Section&nbsp;102(b)(7) of the General Corporation Law of the State of Delaware provides that a
  corporation may eliminate or limit the personal liability of a director to the corporation or its
  stockholders for monetary damages for breach of fiduciary duty as a director, provided that such
  provisions shall not eliminate or limit the liability of a director (i)&nbsp;for any breach of the
  director&#146;s duty of loyalty to the corporation or its stockholders, (ii)&nbsp;for acts or omissions not
  in good faith or which involve intentional misconduct or a knowing violation of law, (iii)&nbsp;under
  section 174 of the General Corporation Law of the State of Delaware regarding the unlawful payment
  of dividends, or (iv)&nbsp;for any transaction from which the director derived an improper personal
  benefit. No such provision shall eliminate or limit the liability of a director for any act or
  omission occurring prior to the date when such provision becomes effective.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Pursuant to the Delaware General Corporation Law, Article&nbsp;VII of the certificate of incorporation
  of the Company eliminates a director&#146;s personal liability for monetary damages to the Company and
  its stockholders for breach of fiduciary duty as a director, except in circumstances involving a
  breach of the director&#146;s duty of loyalty to the Company or its stockholders, acts or omissions not
  in good faith, intentional misconduct, knowing violations of the law, self-dealing or the unlawful
  payment of dividends or repurchase of stock.
  </DIV>
  
  <!-- link2 "ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED" -->
  <DIV align="left"><A NAME="008"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Not applicable.
  </DIV>
  
  <!-- link2 "ITEM 8. EXHIBITS" -->
  <DIV align="left"><A NAME="009"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 8. EXHIBITS.</B>
  </DIV>
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="8%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="89%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description</B></TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit
  3.1 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for the year ended December&nbsp;31, 2001).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.2
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Designation, Preferences and Rights of Series&nbsp;A Convertible Preferred Stock of Inverness
  Medical Innovations, Inc. (incorporated by reference to Exhibit&nbsp;99.2 to the Company&#146;s Current Report on
  Form&nbsp;8-K dated December&nbsp;20, 2001).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.3
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Amended and Restated By-Laws of the Company (incorporated by reference to Exhibit&nbsp;3.3 to the Company&#146;s
  Annual Report on Form&nbsp;10-K, as amended, for the year ended December&nbsp;31, 2001).</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="8%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="89%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description</B></TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.4
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Amendment of Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit&nbsp;3.4 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for
  the year ended December&nbsp;31, 2006).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.5
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Correction to the Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit&nbsp;3.5 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for
  the year ended December&nbsp;31, 2006).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*4.6
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*4.7
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Biosite Incorporated 2002 Nonqualified Stock Incentive Plan.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*5.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Opinion of Jay McNamara, Esq, Senior Counsel, Corporate &#038; Finance, of Inverness Medical Innovations, Inc.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*23.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of BDO Seidman, LLP</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*23.2
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of Colby &#038; Company, PLLC</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;23.4
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of Jay McNamara, Esq., Senior Counsel, Corporate &#038; Finance, of Inverness Medical Innovations,
  Inc. (included in Exhibit&nbsp;5.1)</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;24.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Power of Attorney (contained in signature page)</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  <DIV align="left">
  <DIV style="font-size: 3pt; margin-top: 16pt; width: 18%;  border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV>
  
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">*&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Filed herewith.
  </DIV>
  <!-- link2 "ITEM 9. UNDERTAKINGS" -->
  <DIV align="left"><A NAME="010"></A></DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>ITEM 9. UNDERTAKINGS.</B>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">The registrant hereby undertakes:
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(a)&nbsp;To file, during any period in which offers or sales are being made, a post-effective amendment
  to this registration statement:
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(i)&nbsp;To include any prospectus required by Section&nbsp;10(a)(3) of the Securities Act of 1933, as
  amended (the &#147;Securities Act&#148;);
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(ii)&nbsp;To reflect in the prospectus any facts or events arising after the effective date of the
  registration statement (or the most recent post-effective amendment thereof) which, individually or
  in the aggregate, represent a fundamental change in the information set forth in the registration
  statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered
  (if the total dollar value of securities offered would not exceed that which was registered) and
  any deviation from the low or high end of the estimated maximum offering range may be reflected in
  the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
  changes in volume and price represent no more than a 20&nbsp;percent change in the maximum aggregate
  offering price set forth in the &#147;Calculation of Registration Fee&#148; table in the effective
  registration statement.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(iii)&nbsp;To include any material information with respect to the plan of distribution not previously
  disclosed in the registration statement or any material change to such information in the
  registration statement;
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Provided, however, that paragraphs(a)(i) and (a)(ii) do not apply if the information required
  to be included in a post-effective amendment by those paragraphs is contained in periodic reports
  filed with or furnished to the Commission by the registrant pursuant to Section&nbsp;13 or 15(d) of the
  Exchange Act that are incorporated by reference in the registration statement.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(b)&nbsp;That, for the purpose of determining any liability under the Securities Act, each such
  post-effective amendment will be deemed to be a new registration statement relating to the
  securities offered therein, and the offering of such securities at that time shall be deemed to be
  the initial bona fide offering thereof.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">(c)&nbsp;To remove from registration by means of a post-effective amendment any of the securities being
  registered which remain unsold at the termination of the offering.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">The undersigned registrant hereby undertakes that, for purposes of determining any liability under
  the Securities Act, each filing of the registrant&#146;s annual report pursuant to Section 13(a) or
  Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan&#146;s
  annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in
  the registration statement will be deemed to be a new registration statement relating to the
  securities offered therein, and the offering of such securities at that time will be deemed to be
  the initial bona fide offering thereof.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">Insofar as indemnification for liabilities arising under the Securities Act may be permitted to
  directors, officers and controlling persons of the registrant pursuant to the foregoing provisions,
  or otherwise, the registrant has been advised that in the opinion of the Commission such
  indemnification is against public policy as expressed in the Securities Act and is, therefore,
  unenforceable. In the event that a claim for indemnification against such liabilities (other than
  the payment by the registrant of expenses incurred or paid by a director, officer or controlling
  person of the registrant in the successful defense of any action, suit or proceeding) is asserted
  by such director, officer or controlling person in connection with the securities being registered,
  the registrant will, unless in the opinion of its counsel the matter has been settled by
  controlling precedent, submit to a court of appropriate jurisdiction the question whether such
  indemnification by it is against public policy as expressed in the Securities Act and will be
  governed by the final adjudication of such issue.
  </DIV>
  
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio --><!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  
  <!-- link1 "SIGNATURES" -->
  <DIV align="left"><A NAME="011"></A></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>SIGNATURES</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it
  has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
  has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the City of Waltham, The Commonwealth
  of Massachusetts, on July&nbsp;2,
  2007.
  </DIV>
  
  <TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
  <TR>
      <TD width="48%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="35%">&nbsp;</TD>
      <TD width="15%">&nbsp;</TD>
  </TR>
  <TR>
      <TD valign="top" align="left">&nbsp;</TD>
      <TD colspan="3" align="left"><B>INVERNESS MEDICAL INNOVATIONS, INC.</B><BR>
  &nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD valign="top">By:&nbsp;&nbsp;</TD>
      <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ Ron Zwanziger
  &nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD colspan="2" align="left">Ron Zwanziger&nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD colspan="2" align="left">Chairman, Chief Executive Officer and President&nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR>
  <TR>
      <TD colspan="5">&nbsp;</TD>
  </TR>
  </TABLE>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>POWER OF ATTORNEY</B>
  </DIV>
  
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;KNOW ALL BY THESE PRESENTS that each individual whose signature appears below constitutes and
  appoints each of Ron Zwanziger and David Teitel as such person&#146;s true and lawful attorney-in-fact
  and agent with full power of substitution and resubstitution, for such person in such person&#146;s
  name, place and stead, in any and all capacities, to sign any and all amendments (including
  post-effective amendments) to this registration statement (or any registration statement for the
  same offering that is to be effective upon filing pursuant to Rule 462(b) under the Securities Act
  of 1933), and to file the same, with all exhibits thereto, and all documents in connection
  therewith, with the Securities and Exchange Commission, granting unto each said attorney-in-fact
  and agent full power and authority to do and perform each and every act and thing requisite and
  necessary to be done in and about the premises, as fully to all intents and purposes as such
  person might or could do in person, hereby ratifying and confirming all that any said
  attorney-in-fact and agent, or any substitute or substitutes of any of them, may lawfully do or
  cause to be done by virtue hereof.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has
  been signed by the following persons in the capacities and on the dates indicated.
  </DIV>
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="40%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="40%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="14%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Signature</B></TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Title</B></TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Date</B></TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Ron Zwanziger
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>Ron Zwanziger
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Chairman, Chief Executive
  Officer and President<BR>
  
  (Principal Executive Officer)&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top" nowrap>July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ David Teitel
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>David Teitel
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top" NOWRAP>Chief Financial Officer<BR>
  
  (Principal Financial Officer
  and Principal Accounting
  Officer)&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top" nowrap>July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Carol R. Goldberg
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Carol R. Goldberg</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Robert P. Khederian
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Robert P. Khederian</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ John F. Levy
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">John F. Levy</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Jerry McAleer, Ph.D.
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Jerry McAleer, Ph.D.</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ John A. Quelch
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">John A. Quelch</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ David Scott, Ph.D.
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">David Scott, Ph.D.</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Peter Townsend
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Peter Townsend</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Alfred M. Zeien
  <DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Director&nbsp;
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">July&nbsp;2, 2007</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Alfred M. Zeien</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  <!-- link1 "EXHIBIT INDEX" -->
  <DIV align="left"><A NAME="012"></A></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>EXHIBIT INDEX</B>
  </DIV>
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="8%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="89%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description</B></TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit
  3.1 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for the year ended December&nbsp;31, 2001).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.2
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Designation, Preferences and Rights of Series&nbsp;A Convertible Preferred Stock of Inverness
  Medical Innovations, Inc. (incorporated by reference to Exhibit&nbsp;99.2 to the Company&#146;s Current Report on
  Form&nbsp;8-K dated December&nbsp;20, 2001).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.3
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Amended and Restated By-Laws of the Company (incorporated by reference to Exhibit&nbsp;3.3 to the Company&#146;s
  Annual Report on Form&nbsp;10-K, as amended, for the year ended December&nbsp;31, 2001).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.4
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Amendment of Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit&nbsp;3.4 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for
  the year ended December&nbsp;31, 2006).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;4.5
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Certificate of Correction to the Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit&nbsp;3.5 to the Company&#146;s Annual Report on Form&nbsp;10-K, as amended, for
  the year ended December&nbsp;31, 2006).</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*4.6
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*4.7
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Biosite Incorporated 2002 Nonqualified Stock Incentive Plan.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*5.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Opinion of Jay McNamara, Esq, Senior Counsel, Corporate &#038; Finance, of Inverness Medical Innovations, Inc.</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*23.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of BDO Seidman, LLP</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">*23.2
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of Colby &#038; Company, PLC</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;23.4
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Consent of Jay McNamara, Esq., Senior Counsel, Corporate &#038; Finance, of Inverness Medical Innovations,
  Inc. (included in Exhibit&nbsp;5.1)</TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom">
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;24.1
  </DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">Power of Attorney (contained in signature page)</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
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  <DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
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  <TR valign="top">
      <TD nowrap align="left">*</TD>
      <TD>&nbsp;</TD>
      <TD>Filed herewith.</TD>
  </TR>
  
  </TABLE>
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio --><!-- /Folio -->
  </DIV>
  
  </BODY>
  </HTML>
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text: sv8
  Table of Contents
  As
  filed with the Securities and Exchange Commission on July 2, 2007
  Registration Statement No. 333-
  UNITED STATES SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT
  UNDER
  THE SECURITIES ACT OF 1933
  INVERNESS MEDICAL INNOVATIONS, INC.
  (Exact Name of Registrant as Specified in Its Charter)
  Delaware
  51 Sawyer Road, Suite 200
  Waltham, Massachusetts 02453
  (781) 647-3900
  04-3565120
  (State of Incorporation)
  (Address of Registrant's
  Principal Executive
  Offices)
  (I.R.S. Employer
  Identification No.)
  Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan
  Biosite Incorporated 2002 Nonqualified Stock Incentive Plan
  (Full Title of the Plans)
  Ron Zwanziger
  Chairman, Chief Executive Officer and President
  Inverness Medical Innovations, Inc.
  51 Sawyer Road, Suite 200
  Waltham, Massachusetts 02453
  (781) 647-3900
  (Name, address, including zip code, and telephone number, including area code, of agent for service)
  With copy to:
  Jay McNamara, Esq.
  Senior Counsel, Corporate & Finance
  Inverness Medical Innovations, Inc.
  51 Sawyer Road, Suite 200
  Waltham, Massachusetts 02453
  (781) 647-3900
  CALCULATION OF REGISTRATION FEE
  Proposed Maximum
  Proposed Maximum
  Title of Securities
  Amounts to be
  Offering Price
  Aggregate Offering
  Amount of
  Being Registered
  Registered (1)
  Per Share(2)
  Price(2)
  Registration Fee(2)
  Common Stock, par
  value $.001 per
  share
  1,051,317 shares(3)
  $25.73
  $27,050,386.41
  $830.45
  Common Stock, par
  value $.001 per
  share
  1,060,253 shares(4)
  $28.16
  $29,856,724.48
  $916.60
  (1)
  This registration statement also relates to such indeterminate number of additional shares of
  the registrant's Common Stock as may be required pursuant to the Biosite Incorporated Amended
  and Restated 1996 Stock Incentive Plan, and the Biosite Incorporated 2002 Nonqualified Stock
  Incentive Plan in the event of a stock dividend, stock split, split-up, recapitalization,
  forfeiture of stock under the plan or other similar event.
  (2)
  This estimate is made pursuant to Rule 457(h) under the Securities Act of 1933, as
  amended, solely for the purposes of determining the amount of the
  registration fee. The aggregate offering price and the amount of the registration fee
  under each plan were calculated using the weighted average exercise
  price at which the options may be exercised.
  (3)
  Represents shares of Inverness Medical Innovations, Inc. common stock issuable upon
  exercise of outstanding stock options granted pursuant to the Biosite Incorporated Amended and
  Restated 1996 Stock Incentive Plan.
  (4)
  Represents shares of Inverness Medical Innovations, Inc. common stock issuable upon
  exercise of outstanding stock options granted pursuant to the Biosite Incorporated 2002
  Nonqualified Stock Incentive Plan.
  TABLE OF CONTENTS
  PART I
  ITEM 1. PLAN INFORMATION*
  ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION*
  PART II
  ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE
  ITEM 4. DESCRIPTION OF SECURITIES
  ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
  ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
  ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED
  ITEM 8. EXHIBITS
  ITEM 9. UNDERTAKINGS
  SIGNATURES
  EXHIBIT INDEX
  Ex-4.6 Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan
  Ex-4.7 Biosite Incorporated 2002 Nonqualified Stock Incentive Plan
  Ex-5.1 Opinion of Jay McNamara, Esq
  Ex-23.1 Consent of BDO Seidman, LLP
  Ex-23.2 Consent of Colby & Company, PLC
  Table of Contents
  PART I
  INFORMATION REQUIRED IN THE 10(a) PROSPECTUS
  ITEM 1. PLAN INFORMATION.*
  ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.*
  *Information required by Part I to be contained in the Section 10(a) prospectus is omitted from
  this registration statement in accordance with Rule 428 under the Securities Act of 1933, as
  amended (the "Securities Act"), and the Introductory Note to Part I of Form S-8.
  PART II
  INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
  ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.
  The following documents filed with the Securities and Exchange Commission (the "Commission") are
  incorporated in this registration statement by reference:
  (a) the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2006, filed
  with the Commission on March 1, 2007;
  (b) the Company's Amended Annual Report on Form 10-K/A for the fiscal year ended December 31, 2006,
  filed with the Commission on March 26, 2007;
  (c) the Company's Quarterly Report on Form 10-Q for the quarter ended March 31, 2007, filed with
  the Commission on May 10, 2007;
  (d) the Company's Current Report on Form 8-K filed with the Commission on June 12, 2007;
  (e) the Company's Current Report on Form 8-K filed with the Commission on June 12, 2007;
  (f) the Company's Current Report on Form 8-K filed with the Commission on June 4, 2007;
  (g) the Company's Current Report on Form 8-K filed with the Commission on May 29, 2007;
  (h) the Company's Current Report on Form 8-K filed with the Commission on May 23, 2007;
  (i) the Company's Current Report on Form 8-K filed with the Commission on May 18, 2007;
  (j) the Company's Current Report on Form 8-K filed with the Commission on May 15, 2007;
  (k) the Company's Current Report on Form 8-K filed with the Commission on May 15, 2007;
  (l) the Company's Current Report on Form 8-K filed with the Commission on May 11, 2007;
  (m) the Company's Current Report on Form 8-K filed with the Commission on May 10, 2007;
  (n) the Company's Current Report on Form 8-K filed with the Commission on April 30, 2007;
  (o) the Company's Current Report on Form 8-K filed with the Commission on April 5, 2007;
  (p) the Company's Current Report on Form 8-K filed with the Commission on March 16, 2007, as
  amended by the Company's Current Report on Form 8-K/A filed with the Commission on April 23, 2007;
  (q) the Company's Current Report on Form 8-K filed with the Commission on January 26, 2007; and
  (r) the description of the Company's common stock contained in its Registration Statement on Form
  8-A filed with the Commission on November 21, 2001, as amended, under Section 12 of the Securities
  Exchange Act of 1934, as amended (the "Exchange Act") and any amendments or reports filed for the
  purpose of updating such description.
  In addition, all documents subsequently filed with the Commission by the Company pursuant to
  Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
  amendment hereto which indicates that all securities offered have been sold or which deregisters
  all securities then remaining unsold, shall be deemed to be incorporated by reference in this
  registration statement and to be part hereof from the date of filing of such documents.
  ITEM 4. DESCRIPTION OF SECURITIES.
  Not applicable.
  Table of Contents
  ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.
  The validity of the securities the Company is offering are being passed upon by Jay McNamara, Esq.,
  Senior Counsel, Corporate & Finance, of the Company. Mr. McNamara owns an aggregate of
  approximately 2,529 shares of common stock of the Company, as well as options to purchase an
  additional 17,579 shares of common stock of the Company.
  ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.
  Section 145 of the Delaware General Corporation Law provides that a corporation may indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or
  completed action, suit or proceeding, whether civil, criminal, administrative or investigative,
  other than an action by or in the right of the corporation, by reason of the fact that the person
  is or was a director, officer, employee or agent of the corporation or is or was serving at the
  corporation's request as a director, officer, employee or agent of another corporation,
  partnership, joint venture, trust or other enterprise, against expenses, including attorneys' fees,
  judgments, fines and amounts paid in settlement actually and reasonably incurred by the person in
  connection with the action, suit or proceeding if the person acted in good faith and in a manner
  the person reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe the
  person's conduct was unlawful. The power to indemnify applies to actions brought by or in the right
  of the corporation as well, but only to the extent of expenses, including attorneys' fees but
  excluding judgments, fines and amounts paid in settlement, actually and reasonably incurred by the
  person in connection with the defense or settlement of the action or suit. And with the further
  limitation that in these actions, no indemnification shall be made in the event of any adjudication
  of negligence or misconduct in the performance of the person's duties to the corporation, unless a
  court believes that in light of all the circumstances indemnification should apply.
  Article V of the Company's by-laws provides that the Company shall, to the extent legally
  permitted, indemnify each person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action, suit or proceeding by reason of the fact that such person
  is or was, or has agreed to become, a director or officer of the Company, or is or was serving, or
  has agreed to serve, at the request of the Company, as a director, officer, trustee, partner,
  employee or agent of, or in a similar capacity with, another corporation, partnership, joint
  venture, trust, employee benefit plan or other enterprise. The indemnification provided for in
  Article V is expressly not exclusive of any other rights to which those seeking indemnification may
  be entitled under any law, agreement or vote of stockholders or disinterested directors or
  otherwise, and shall inure to the benefit of the heirs, executors and administrators of such
  persons.
  Section 145(g) of the Delaware General Corporation Law and Article V of the by-laws of the Company
  provide that the Company shall have the power to purchase and maintain insurance on behalf of its
  officers, directors, employees and agents, against any liability asserted against and incurred by
  such persons in any such capacity.
  The Company has obtained insurance covering its directors and officers against losses and insuring
  the Company against certain of its obligations to indemnify its directors and officers.
  Section 102(b)(7) of the General Corporation Law of the State of Delaware provides that a
  corporation may eliminate or limit the personal liability of a director to the corporation or its
  stockholders for monetary damages for breach of fiduciary duty as a director, provided that such
  provisions shall not eliminate or limit the liability of a director (i) for any breach of the
  director's duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not
  in good faith or which involve intentional misconduct or a knowing violation of law, (iii) under
  section 174 of the General Corporation Law of the State of Delaware regarding the unlawful payment
  of dividends, or (iv) for any transaction from which the director derived an improper personal
  benefit. No such provision shall eliminate or limit the liability of a director for any act or
  omission occurring prior to the date when such provision becomes effective.
  Pursuant to the Delaware General Corporation Law, Article VII of the certificate of incorporation
  of the Company eliminates a director's personal liability for monetary damages to the Company and
  its stockholders for breach of fiduciary duty as a director, except in circumstances involving a
  breach of the director's duty of loyalty to the Company or its stockholders, acts or omissions not
  in good faith, intentional misconduct, knowing violations of the law, self-dealing or the unlawful
  payment of dividends or repurchase of stock.
  ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.
  Not applicable.
  ITEM 8. EXHIBITS.
  Exhibit No.
  Description
  4.1
  Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit
  3.1 to the Company's Annual Report on Form 10-K, as amended, for the year ended December 31, 2001).
  4.2
  Certificate of Designation, Preferences and Rights of Series A Convertible Preferred Stock of Inverness
  Medical Innovations, Inc. (incorporated by reference to Exhibit 99.2 to the Company's Current Report on
  Form 8-K dated December 20, 2001).
  4.3
  Amended and Restated By-Laws of the Company (incorporated by reference to Exhibit 3.3 to the Company's
  Annual Report on Form 10-K, as amended, for the year ended December 31, 2001).
  Table of Contents
  Exhibit No.
  Description
  4.4
  Certificate of Amendment of Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit 3.4 to the Company's Annual Report on Form 10-K, as amended, for
  the year ended December 31, 2006).
  4.5
  Certificate of Correction to the Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit 3.5 to the Company's Annual Report on Form 10-K, as amended, for
  the year ended December 31, 2006).
  *4.6
  Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan.
  *4.7
  Biosite Incorporated 2002 Nonqualified Stock Incentive Plan.
  *5.1
  Opinion of Jay McNamara, Esq, Senior Counsel, Corporate & Finance, of Inverness Medical Innovations, Inc.
  *23.1
  Consent of BDO Seidman, LLP
  *23.2
  Consent of Colby & Company, PLLC
  23.4
  Consent of Jay McNamara, Esq., Senior Counsel, Corporate & Finance, of Inverness Medical Innovations,
  Inc. (included in Exhibit 5.1)
  24.1
  Power of Attorney (contained in signature page)
  *     Filed herewith.
  ITEM 9. UNDERTAKINGS.
  The registrant hereby undertakes:
  (a) To file, during any period in which offers or sales are being made, a post-effective amendment
  to this registration statement:
  (i) To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933, as
  amended (the "Securities Act");
  (ii) To reflect in the prospectus any facts or events arising after the effective date of the
  registration statement (or the most recent post-effective amendment thereof) which, individually or
  in the aggregate, represent a fundamental change in the information set forth in the registration
  statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered
  (if the total dollar value of securities offered would not exceed that which was registered) and
  any deviation from the low or high end of the estimated maximum offering range may be reflected in
  the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
  changes in volume and price represent no more than a 20 percent change in the maximum aggregate
  offering price set forth in the "Calculation of Registration Fee" table in the effective
  registration statement.
  (iii) To include any material information with respect to the plan of distribution not previously
  disclosed in the registration statement or any material change to such information in the
  registration statement;
  Provided, however, that paragraphs(a)(i) and (a)(ii) do not apply if the information required
  to be included in a post-effective amendment by those paragraphs is contained in periodic reports
  filed with or furnished to the Commission by the registrant pursuant to Section 13 or 15(d) of the
  Exchange Act that are incorporated by reference in the registration statement.
  (b) That, for the purpose of determining any liability under the Securities Act, each such
  post-effective amendment will be deemed to be a new registration statement relating to the
  securities offered therein, and the offering of such securities at that time shall be deemed to be
  the initial bona fide offering thereof.
  (c) To remove from registration by means of a post-effective amendment any of the securities being
  registered which remain unsold at the termination of the offering.
  The undersigned registrant hereby undertakes that, for purposes of determining any liability under
  the Securities Act, each filing of the registrant's annual report pursuant to Section 13(a) or
  Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's
  annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in
  the registration statement will be deemed to be a new registration statement relating to the
  securities offered therein, and the offering of such securities at that time will be deemed to be
  the initial bona fide offering thereof.
  Insofar as indemnification for liabilities arising under the Securities Act may be permitted to
  directors, officers and controlling persons of the registrant pursuant to the foregoing provisions,
  or otherwise, the registrant has been advised that in the opinion of the Commission such
  indemnification is against public policy as expressed in the Securities Act and is, therefore,
  unenforceable. In the event that a claim for indemnification against such liabilities (other than
  the payment by the registrant of expenses incurred or paid by a director, officer or controlling
  person of the registrant in the successful defense of any action, suit or proceeding) is asserted
  by such director, officer or controlling person in connection with the securities being registered,
  the registrant will, unless in the opinion of its counsel the matter has been settled by
  controlling precedent, submit to a court of appropriate jurisdiction the question whether such
  indemnification by it is against public policy as expressed in the Securities Act and will be
  governed by the final adjudication of such issue.
  Table of Contents
  SIGNATURES
  Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it
  has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
  has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the City of Waltham, The Commonwealth
  of Massachusetts, on July 2,
  2007.
  INVERNESS MEDICAL INNOVATIONS, INC.
  By:
  /s/ Ron Zwanziger
  Ron Zwanziger
  Chairman, Chief Executive Officer and President
  POWER OF ATTORNEY
  KNOW ALL BY THESE PRESENTS that each individual whose signature appears below constitutes and
  appoints each of Ron Zwanziger and David Teitel as such person's true and lawful attorney-in-fact
  and agent with full power of substitution and resubstitution, for such person in such person's
  name, place and stead, in any and all capacities, to sign any and all amendments (including
  post-effective amendments) to this registration statement (or any registration statement for the
  same offering that is to be effective upon filing pursuant to Rule 462(b) under the Securities Act
  of 1933), and to file the same, with all exhibits thereto, and all documents in connection
  therewith, with the Securities and Exchange Commission, granting unto each said attorney-in-fact
  and agent full power and authority to do and perform each and every act and thing requisite and
  necessary to be done in and about the premises, as fully to all intents and purposes as such
  person might or could do in person, hereby ratifying and confirming all that any said
  attorney-in-fact and agent, or any substitute or substitutes of any of them, may lawfully do or
  cause to be done by virtue hereof.
  Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has
  been signed by the following persons in the capacities and on the dates indicated.
  Signature
  Title
  Date
  /s/ Ron Zwanziger
  Ron Zwanziger
  Chairman, Chief Executive
  Officer and President
  (Principal Executive Officer)
  July 2, 2007
  /s/ David Teitel
  David Teitel
  Chief Financial Officer
  (Principal Financial Officer
  and Principal Accounting
  Officer)
  July 2, 2007
  /s/ Carol R. Goldberg
  Director
  July 2, 2007
  Carol R. Goldberg
  /s/ Robert P. Khederian
  Director
  July 2, 2007
  Robert P. Khederian
  /s/ John F. Levy
  Director
  July 2, 2007
  John F. Levy
  /s/ Jerry McAleer, Ph.D.
  Director
  July 2, 2007
  Jerry McAleer, Ph.D.
  /s/ John A. Quelch
  Director
  July 2, 2007
  John A. Quelch
  /s/ David Scott, Ph.D.
  Director
  July 2, 2007
  David Scott, Ph.D.
  /s/ Peter Townsend
  Director
  July 2, 2007
  Peter Townsend
  /s/ Alfred M. Zeien
  Director
  July 2, 2007
  Alfred M. Zeien
  Table of Contents
  EXHIBIT INDEX
  Exhibit No.
  Description
  4.1
  Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit
  3.1 to the Company's Annual Report on Form 10-K, as amended, for the year ended December 31, 2001).
  4.2
  Certificate of Designation, Preferences and Rights of Series A Convertible Preferred Stock of Inverness
  Medical Innovations, Inc. (incorporated by reference to Exhibit 99.2 to the Company's Current Report on
  Form 8-K dated December 20, 2001).
  4.3
  Amended and Restated By-Laws of the Company (incorporated by reference to Exhibit 3.3 to the Company's
  Annual Report on Form 10-K, as amended, for the year ended December 31, 2001).
  4.4
  Certificate of Amendment of Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit 3.4 to the Company's Annual Report on Form 10-K, as amended, for
  the year ended December 31, 2006).
  4.5
  Certificate of Correction to the Amended and Restated Certificate of Incorporation of the Company
  (incorporated by reference to Exhibit 3.5 to the Company's Annual Report on Form 10-K, as amended, for
  the year ended December 31, 2006).
  *4.6
  Biosite Incorporated Amended and Restated 1996 Stock Incentive Plan.
  *4.7
  Biosite Incorporated 2002 Nonqualified Stock Incentive Plan.
  *5.1
  Opinion of Jay McNamara, Esq, Senior Counsel, Corporate & Finance, of Inverness Medical Innovations, Inc.
  *23.1
  Consent of BDO Seidman, LLP
  *23.2
  Consent of Colby & Company, PLC
  23.4
  Consent of Jay McNamara, Esq., Senior Counsel, Corporate & Finance, of Inverness Medical Innovations,
  Inc. (included in Exhibit 5.1)
  24.1
  Power of Attorney (contained in signature page)
  *
  Filed herewith.