content: <PAGE>   1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
                         SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
                             THE SECURITIES ACT OF 1933
  
                                    BIOSEPRA INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                              04-3216867
  (State or other jurisdiction of               (I.R.S. Employer
   incorporation or organization)              Identification No.)
  
                  111 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
              (Address of Principal Executive Offices)       (Zip Code)
  
                              1994 DIRECTOR OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
                           CALCULATION OF REGISTRATION FEE
  
  <TABLE>
  <CAPTION>
                              Proposed   Proposed
  Title of                    maximum    maximum
  securities     Amount       offering   aggregate    Amount of
  to be          to be        price      offering     registration
  registered     registered   per share  price        fee
  - ----------     ----------   ---------  ---------    ------------
  <S>             <C>         <C>        <C>          <C>    
  Common Stock,   30,000      $4.75(1)   $142,500(1)  $100.00
  $.01 par        shares
  value
  </TABLE>
  
  - -------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  <PAGE>   2
  Statement of Incorporation by Reference
  
           This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79396, relating
  to the Registrant's 1994 Director Option Plan.
  
                                        -2-
  <PAGE>   3
                                     SIGNATURES
  
           Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                                   BIOSEPRA INC.
  
                                                By: /s/ Jean-Marie Vogel
                                                   -------------------------------
                                                    Jean-Marie Vogel
                                                    President and
                                                    Chief Executive Officer
  
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of BioSepra Inc. hereby
  severally constitute Jean-Marie Vogel, Peter Castellanos and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable BioSepra Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                       -3-
  <PAGE>   4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  
  <TABLE>
  <CAPTION>
  Signature                                Title                                      Date                
  - ---------                                -----                                      ----                
  <S>                               <C>                                       <C>    <C>                  
  /s/ Jean-Marie Vogel              President, Chief                          )                           
  - -------------------------         Executive Officer                         )                           
  Jean-Marie Vogel                  and Director                              )                           
                                    (Principal Executive                      )                           
                                     and Financial Officer)                   )                           
                                                                              )                           
  /s/ Peter M. Castellanos          Controller  (Principal                    )                           
  - -------------------------         Accounting Officer)                       )                           
  Peter M. Castellanos                                                        )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Timothy J. Barberich          Director                                  )                           
  - -------------------------                                                   )                           
  Timothy J. Barberich                                                        )                           
                                                                              )                           
                                                                              )      June 7, 1996         
                                                                              )                           
  /s/ Robert L. Bratzler            Director                                  )                           
  - -------------------------                                                   )                           
  Robert L. Bratzler, Ph.D.                                                   )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ William M. Cousins, Jr.       Director                                  )                           
  - -------------------------                                                   )                           
  William M. Cousins, Jr.                                                     )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Alexander M. Klibanov         Director                                  )                           
  - -------------------------                                                   )                           
  Alexander M. Klibanov, Ph.D.                                                )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Paul A. Looney                Director                                  )                           
  - -------------------------                                                   )                           
  Paul A. Looney                                                              )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Riccardo Pigliucci            Director                                  )                           
  - -------------------------                                                   )                           
  Riccardo Pigliucci                                                          )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ William E. Rich               Director                                  )                           
  - -------------------------                                                   )                           
  William E. Rich, Ph.D.                                                      )                           
  </TABLE>
  
                                        -4-
  <PAGE>   5
                                    EXHIBIT INDEX
                                    -------------
  <TABLE>
  <CAPTION>
  Exhibit
  Number                 Description                                              Page
  - -------                -----------                                              ----
  <S>                    <C>                                                      <C>    
   4.1                   Certificate of Incorporation
                         of the Registrant, as amended
  
   4.2                   By-Laws of the Registrant
  
   4.3 *                 Specimen Certificate of Common Stock of
                         the Registrant                                             -
  
   5                     Opinion of Hale and Dorr
  
  23.1                   Consent of Hale and Dorr (included in Exhibit 5)           -
  
  23.2                   Consent of Coopers & Lybrand L.L.P.
  
  24                     Power of Attorney (included in the signature pages
                         of this Registration Statement)                            -
  </TABLE>
  
  - --------
  *  Incorporated herein by reference from the Registrant's Registration
  Statement on Form S-1 (File No.  33-75212)
  
                                         -5-
metadata_documents: [{"type": "S-8", "sequence": "1", "description": "BIOSEPRA INC.", "secsgml_size_bytes": 11559}]
metadata_filer: {"company-data": {"conformed-name": "BIOSEPRA INC", "cik": "0000919015", "assigned-sic": "2890", "irs-number": "043216867", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-05621", "film-number": "96578898"}, "business-address": {"street1": "111 LOCKE DR", "city": "MALBOROUGH", "state": "MA", "zip": "01752", "phone": "5084816802"}}
text: 1
                As filed with the Securities and Exchange Commission
                                  on June 10, 1996
  
                         SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
                                      FORM S-8
  
                            REGISTRATION STATEMENT UNDER
                             THE SECURITIES ACT OF 1933
  
                                    BIOSEPRA INC.
               (Exact name of registrant as specified in its charter)
  
             DELAWARE                              04-3216867
  (State or other jurisdiction of               (I.R.S. Employer
   incorporation or organization)              Identification No.)
  
                  111 LOCKE DRIVE, MARLBOROUGH, MASSACHUSETTS 01752
              (Address of Principal Executive Offices)       (Zip Code)
  
                              1994 DIRECTOR OPTION PLAN
                              (Full title of the plan)
  
                                MARK G. BORDEN, ESQ.
                                    HALE AND DORR
                                   60 STATE STREET
                             BOSTON, MASSACHUSETTS 02109
                       (Name and address of agent for service)
  
                                   (617) 526-6000
            (Telephone number, including area code, of agent for service)
  
                           CALCULATION OF REGISTRATION FEE
  Proposed   Proposed
  Title of                    maximum    maximum
  securities     Amount       offering   aggregate    Amount of
  to be          to be        price      offering     registration
  registered     registered   per share  price        fee
  - ----------     ----------   ---------  ---------    ------------
  Common Stock,   30,000      $4.75(1)   $142,500(1)  $100.00
  $.01 par        shares
  value
  - -------------------------------------------------------------------
  (1)      Estimated solely for the purpose of calculating the registration fee,
           and based upon the average of the high and low prices of the Common
           Stock on the Nasdaq National Market on June 3, 1996 in accordance with
           Rules 457(c) and 457(h) of the Securities Act of 1933.
  2
  Statement of Incorporation by Reference
  
           This Registration Statement on Form S-8 incorporates by reference the
  contents of the Registration Statement on Form S-8, File No. 33-79396, relating
  to the Registrant's 1994 Director Option Plan.
  
                                        -2-
  3
                                     SIGNATURES
  
           Pursuant to the requirements of the Securities Act, the Registrant
  certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration
  Statement to be signed on its behalf by the undersigned, thereunto duly
  authorized, in the Town of Marlborough, Commonwealth of Massachusetts on the 7th
  day of June, 1996.
  
                                                   BIOSEPRA INC.
  
                                                By: /s/ Jean-Marie Vogel
                                                   -------------------------------
                                                    Jean-Marie Vogel
                                                    President and
                                                    Chief Executive Officer
  
                                  POWER OF ATTORNEY
  
           We, the undersigned officers and directors of BioSepra Inc. hereby
  severally constitute Jean-Marie Vogel, Peter Castellanos and Mark G. Borden, and
  each of them singly, our true and lawful attorneys with full power to them, and
  each of them singly, to sign for us and in our names in the capacities indicated
  below, the Registration Statement on Form S-8 filed herewith and any and all
  subsequent amendments to said Registration Statement, and generally to do all
  such things in our names and behalf in our capacities as officers and directors
  to enable BioSepra Inc. to comply with all requirements of the Securities and
  Exchange Commission, hereby ratifying and confirming our signatures as they may
  be signed by said attorneys, or any of them, to said Registration Statement and
  any and all amendments thereto.
  
                                       -3-
  4
           Pursuant to the requirements of the Securities Act, this Registration
  Statement has been signed below by the following persons in the capacities and
  on the date indicated.
  Signature                                Title                                      Date                
  - ---------                                -----                                      ----
  /s/ Jean-Marie Vogel              President, Chief                          )                           
  - -------------------------         Executive Officer                         )                           
  Jean-Marie Vogel                  and Director                              )                           
                                    (Principal Executive                      )                           
                                     and Financial Officer)                   )                           
                                                                              )                           
  /s/ Peter M. Castellanos          Controller  (Principal                    )                           
  - -------------------------         Accounting Officer)                       )                           
  Peter M. Castellanos                                                        )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Timothy J. Barberich          Director                                  )                           
  - -------------------------                                                   )                           
  Timothy J. Barberich                                                        )                           
                                                                              )                           
                                                                              )      June 7, 1996         
                                                                              )                           
  /s/ Robert L. Bratzler            Director                                  )                           
  - -------------------------                                                   )                           
  Robert L. Bratzler, Ph.D.                                                   )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ William M. Cousins, Jr.       Director                                  )                           
  - -------------------------                                                   )                           
  William M. Cousins, Jr.                                                     )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Alexander M. Klibanov         Director                                  )                           
  - -------------------------                                                   )                           
  Alexander M. Klibanov, Ph.D.                                                )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Paul A. Looney                Director                                  )                           
  - -------------------------                                                   )                           
  Paul A. Looney                                                              )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ Riccardo Pigliucci            Director                                  )                           
  - -------------------------                                                   )                           
  Riccardo Pigliucci                                                          )                           
                                                                              )                           
                                                                              )                           
                                                                              )                           
  /s/ William E. Rich               Director                                  )                           
  - -------------------------                                                   )                           
  William E. Rich, Ph.D.                                                      )
  -4-
  5
                                    EXHIBIT INDEX
                                    -------------
  Exhibit
  Number                 Description                                              Page
  - -------                -----------                                              ----
  4.1                   Certificate of Incorporation
                         of the Registrant, as amended
  
   4.2                   By-Laws of the Registrant
  
   4.3 *                 Specimen Certificate of Common Stock of
                         the Registrant                                             -
  
   5                     Opinion of Hale and Dorr
  
  23.1                   Consent of Hale and Dorr (included in Exhibit 5)           -
  
  23.2                   Consent of Coopers & Lybrand L.L.P.
  
  24                     Power of Attorney (included in the signature pages
                         of this Registration Statement)                            -
  - --------
  *  Incorporated herein by reference from the Registrant's Registration
  Statement on Form S-1 (File No.  33-75212)
  
                                         -5-