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  <DIV align="center" style="font-size: 10pt; margin-top: 18pt">As filed with the Securities and Exchange Commission on March 13, 2009
  </DIV>
  
  
  <DIV align="right" style="font-size: 10pt; margin-top: 0pt">Registration No.&nbsp;333-<U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U>
  </DIV>
  
  
  <DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt; margin-top=6pt">&nbsp;</DIV>
  <DIV style="width: 100%; border-bottom: 1pt solid black; font-size: 1pt">&nbsp;</DIV>
  
  
  
  
  <DIV align="center" style="font-size: 14pt; margin-top: 12pt"><B>UNITED STATES<BR>
  SECURITIES AND EXCHANGE COMMISSION</B>
  </DIV>
  
  <DIV align="center" style="font-size: 12pt"><B>Washington, D.C. 20549</B>
  </DIV>
  
  <DIV align="center" style="font-size: 12pt"><B><DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></B>
  </DIV>
  
  <DIV align="center" style="font-size: 18pt; margin-top: 12pt"><B>FORM S-8</B>
  </DIV>
  
  
  <DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>REGISTRATION STATEMENT<BR>
  UNDER<BR>
  THE SECURITIES ACT OF 1933</B>
  </DIV>
  
  
  <DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B><DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></B>
  </DIV>
  
  <DIV align="center" style="font-size: 24pt; margin-top: 12pt"><B>SeraCare Life Sciences, Inc.</B>
  </DIV>
  
  <DIV align="center" style="font-size: 10pt">(Exact name of registrant as specified in its charter)</DIV>
  
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="47%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="47%">&nbsp;</TD>
  </TR>
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  <!-- Begin Table Body -->
  <TR valign="bottom">
      <TD align="center" valign="top">Delaware<BR>
  (State or other jurisdiction <BR>
  of incorporation or organization)
  </TD>
      <TD>&nbsp;</TD>
      <TD align="center" valign="top">33-0056054<BR>
  (I.R.S. Employer<BR>
  Identification No.)</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>37 Birch Street<BR>
  Milford, MA 01757<BR>
  (508)&nbsp;244-6400</B><BR>
  (Address of principal executive offices, including zip code)</DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt"><DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>2009 Equity Incentive Plan</B><BR>
  (Full title of the plans)</DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt"><DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt">Gregory A. Gould<BR>
  37 Birch Street<BR>
  Milford, MA 01757<BR>
  (508)&nbsp;244-6400<BR>
  (Name, address and telephone number, including area code, of agent for service)</DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt"><DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 12pt">Please send copies of all communications to:<BR>
  Hemmie Chang, Esq.<BR>
  Ropes &#038; Gray LLP<BR>
  One International Place<BR>
  Boston, MA 02110<BR>
  617-951-7000<BR>
  617-951-7050 (facsimile)</DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Indicate by check
  mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a
  smaller reporting company. See the definitions of &#147;large accelerated filer,&#148; &#147;accelerated filer&#148;
  and &#147;smaller reporting company&#148; in Rule 12b-2 of the Exchange Act. (Check one):
  </DIV>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 0pt"><TABLE width="100%" style="font-size: 10pt; margin-top: 6pt"><TR>
  <TD valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Large accelerated filer&nbsp;<FONT face="Wingdings">&#111;</FONT></TD>
  <TD valign="top" align="center">Accelerated filer&nbsp;<FONT face="Wingdings">&#111;</FONT>&nbsp;</TD>
  <TD align="center">Non-accelerated filer&nbsp;<FONT face="Wingdings">&#254;</FONT><BR>(Do not check if a smaller reporting company)</TD>
  <TD valign="top" align="right">Smaller reporting company&nbsp;<FONT face="Wingdings">&#111;</FONT></TD></TR></TABLE>
  </DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>CALCULATION OF REGISTRATION FEE</B>
  </DIV>
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom" style="font-size: 1px">
      <TD width="1%">&nbsp;</TD>
      <TD width="22%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD><!-- VRule -->
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="2%">&nbsp;</TD>
  
      <TD width="1%">&nbsp;</TD>
  </TR><TR style="font-size: 1px" valign="bottom">
      <TD nowrap align="left" colspan="23" style="border-bottom: 3px double #000000">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD>&nbsp;</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">Proposed</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">Proposed</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD nowrap align="center">Title of</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">maximum</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">maximum</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD nowrap align="center">securities to be</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">Amount to be</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">offering</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">aggregate</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">Amount of</TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>
  
      <TD nowrap align="center">registered</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">registered (1)</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">price per share (2)</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">offering price (2)</TD>
      <TD style="border-right: 2px solid #000000">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="center" colspan="3">registration fee</TD>
      <TD width="1%">&nbsp;</TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
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      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
                      <TD style="border-top: 2px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock, par value $0.001 per share</DIV></TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD align="right" style="border-top: 2px solid #000000">1,500,000</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD align="right" style="border-top: 2px solid #000000">$</TD>
      <TD align="right" style="border-top: 2px solid #000000">0.52</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD align="right" style="border-top: 2px solid #000000">$</TD>
      <TD align="right" style="border-top: 2px solid #000000">780,000</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD align="right" style="border-top: 2px solid #000000">$</TD>
      <TD align="right" style="border-top: 2px solid #000000">30.65</TD>
      <TD style="border-top: 2px solid #000000">&nbsp;</TD>
      <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
  </TR>
  <TR style="font-size: 1px" valign="bottom">
      <TD nowrap align="left" colspan="23" style="border-top: 3px double #000000">&nbsp;</TD>
  </TR>
  
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  <TR>
      <TD width="3%"></TD>
      <TD width="1%"></TD>
      <TD width="96"></TD>
  </TR>
  <TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>
  
  <TR valign="top">
      <TD nowrap align="left">(1)</TD>
      <TD>&nbsp;</TD>
      <TD>This Registration Statement covers an aggregate of 1,500,000 shares of the Registrant&#146;s
  common stock, par value $0.001 per share (the &#147;Common Stock&#148;), that may be issued pursuant to
  awards granted under the equity plan identified above (the &#147;Plan&#148;). In addition, pursuant to
  Rule 416(a) under the Securities Act of 1933, as amended (the &#147;Securities Act of 1933&#148;) this
  Registration Statement also covers such additional shares of Common Stock as may be issued
  pursuant to the antidilution provisions of the Plan to which this Registration Statement
  relates.</TD>
  </TR>
  
  <TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>
  
  <TR valign="top">
      <TD nowrap align="left">(2)</TD>
      <TD>&nbsp;</TD>
      <TD>Estimated solely for the purposes of calculating the amount of registration fee. In
  accordance with Rule 457(h) and (c)&nbsp;of the Securities Act of 1933, as amended, the price shown
  is the average high and low selling prices of the common stock for March 9, 2009 as
  reported on the NASDAQ Capital Market.</TD>
  </TR>
  
  </TABLE>
  
  
  
  <DIV style="width: 100%; border-bottom: 1pt solid black; margin-top: 10pt; font-size: 1pt">&nbsp;</DIV>
  <DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>
  
  
  
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  
  
  
  
  
  <!-- link1 "PART I" -->
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART I</B>
  </DIV>
  
  
  <DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B>
  
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The information required by Item&nbsp;1 has been sent or given to employees as specified by Rule
  428(b)(1). Such documents are not being filed with the Securities and Exchange Commission (the
  &#147;Commission&#148;) either as part of this Registration Statement or as prospectuses or prospectus
  supplements pursuant to Rule&nbsp;424. Such documents and the documents incorporated by reference in
  this Registration Statement pursuant to Item&nbsp;3 of Part&nbsp;II of this Form, taken together, constitute
  a prospectus that meets the requirements of Section 10(a) of the Securities Act.
  </DIV>
  <!-- link1 "PART II<BR> INFORMATION REQUIRED IN THE REGISTRATION STATEMENT" -->
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART II<BR>
  INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>
  </DIV>
  
  <!-- link2 "Item&nbsp;3. Incorporation of Documents by Reference." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;3. Incorporation of Documents by Reference.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;SeraCare Life Sciences, Inc. (the &#147;Registrant&#148;) hereby incorporates the following documents
  herein by reference:
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(a)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The Registrant&#146;s latest annual report on Form 10-K for the fiscal year ended
  September&nbsp;30, 2008, filed with the Commission pursuant to the Securities Exchange Act
  of 1934, as amended (the &#147;Exchange Act&#148;), on December&nbsp;8, 2008.</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(b)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The Registrant&#146;s Quarterly Report for the quarter ended December&nbsp;31, 2008 on
  Form 10-Q filed on February&nbsp;17, 2009.</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(c)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The Registrant&#146;s Current Reports on Form 8-K filed on December&nbsp;8, 2008,
  December&nbsp;22, 2008 and February&nbsp;17, 2009.</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(d)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The description of the Common Stock, $0.001 par value per share, contained in
  Item&nbsp;1 of the Registrant&#146;s Registration Statement on Form 8-A, filed with the
  Commission pursuant to Section&nbsp;12 of the Exchange Act on June&nbsp;20, 2008.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents subsequently filed by the Registrant pursuant to Sections&nbsp;13(a), 13(c), 14 and
  15(d) of the Exchange Act, prior to the filing of a post-effective amendment to this Registration
  Statement that indicates that all securities offered have been sold or which deregisters all
  securities then remaining unsold, shall be deemed to be incorporated herein by reference from the
  date of filing of such documents.
  </DIV>
  <!-- link2 "Item&nbsp;4. Description of Securities." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;4. Description of Securities.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
  </DIV>
  <!-- link2 "Item&nbsp;5. Interests of Named Experts and Counsel." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;5. Interests of Named Experts and Counsel.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
  </DIV>
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
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  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  <!-- link2 "Item&nbsp;6. Indemnification of Directors and Officers." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;6. Indemnification of Directors and Officers.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant is incorporated under the laws of the State of Delaware. Section&nbsp;145 (&#147;Section
  145&#148;) of the General Corporation Law of the State of Delaware, as the same exists or may hereafter
  be amended (the &#147;General Corporation Law&#148;), inter alia, provides that a Delaware corporation may
  indemnify any persons who were, are or are threatened to be made, parties to any threatened,
  pending or completed action, suit or proceeding, whether civil, criminal, administrative or
  investigative (other than an action by or in the right of such corporation), by reason of the fact
  that such person is or was an officer, director, employee or agent of such corporation, or is or
  was serving at the request of such corporation as a director, officer, employee or agent of another
  corporation or enterprise. The indemnity may include expenses (including attorneys&#146; fees),
  judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in
  connection with such action, suit or proceeding, provided such person acted in good faith and in a
  manner he reasonably believed to be in or not opposed to the corporation&#146;s best interests and, with
  respect to any criminal action or proceeding, had no reasonable cause to believe that his conduct
  was illegal. In addition, the statutes of Delaware contain provisions to the general effect that
  any director shall in the performance of his duties be fully protected in relying in good faith
  upon the books of account or records of the corporation or statements prepared by any official of
  the corporation.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant&#146;s certificate of incorporation provides that the Registrant shall, to the
  fullest extent permitted under and in accordance with the laws of the State of Delaware, indemnify
  any person who was or is a party or is threatened to be made a party to any threatened, pending or
  completed action, suit or proceeding by reason of the fact that he is or was, or has agreed to
  become, a director or officer of the Registrant. The indemnification provided for in the
  Registrant&#146;s certificate of incorporation is expressly not exclusive of any provisions with respect
  thereto in the Registrant&#146;s Bylaws or any other contract or agreement between the Registrant and
  any officer, director, employee or agent of the Registrant.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;145 further authorizes a corporation to purchase and maintain insurance on behalf of
  any person who is or was a director, officer, employee or agent of the corporation, or is or was
  serving at the request of the corporation as a director, officer, employee or agent of another
  corporation or enterprise, against any liability asserted against him and incurred by him in any
  such capacity, arising out of his status as such, whether or not the corporation would otherwise
  have the power to indemnify him under Section&nbsp;145.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We currently have directors&#146; and officers&#146; liability insurance to provide our directors and
  officers with insurance coverage for losses arising from claims based on breaches of duty,
  negligence, errors and other wrongful acts.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;102(b)(7) of the General Corporation Law of the State of Delaware provides that a
  corporation may eliminate or limit the personal liability of a director to the corporation or its
  stockholders for monetary damages for breach of fiduciary duty as a director, provided that such
  provision shall not eliminate or limit the liability of a director (i)&nbsp;for any breach of the
  director&#146;s duty of loyalty to the corporation or its stockholders, (ii)&nbsp;for acts or omissions not
  in good faith or which involve intentional misconduct or a knowing violation of law, (iii)&nbsp;under
  Section&nbsp;174 of the General Corporation Law of the State of Delaware, or (iv)&nbsp;for any transaction
  from which the director derived an improper personal benefit. No such provision shall eliminate or
  limit the liability of a director for any act or omission occurring prior to the date when such
  provision becomes effective.
  </DIV>
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant&#146;s certificate of incorporation provides that the liability of the directors for
  monetary damages shall be eliminated to the fullest extent under applicable law. If the General
  Corporation Law is amended to authorize corporate action further eliminating or limiting the
  personal liability of directors, then the liability of a director of the corporation shall be eliminated to the fullest extent permitted by the General
  Corporation Law, as so amended.
  </DIV>
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->-2-<!-- /Folio -->
  </DIV>
  
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  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  <!-- link2 "Item&nbsp;7. Exemption From Registration Claimed." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;7. Exemption From Registration Claimed.</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
  </DIV>
  <!-- link2 "Item&nbsp;8. Exhibits." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;8. Exhibits.</B>
  </DIV>
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="3%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="88%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" colspan="2">Exhibit</TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom"><!-- Blank Space -->
      <TD nowrap align="right" valign="top">&nbsp;</TD>
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">4.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">2009 Equity Incentive Plan.</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">4.2</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Certificate of Incorporation (previously filed as Exhibit&nbsp;3.1 to the
  Registrant&#146;s Registration Statement on Form&nbsp;8-A filed on May&nbsp;17, 2007).</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">4.3</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Amended and Restated By-laws (previously filed as Exhibit&nbsp;3.1 to the
  Registrant&#146;s Current Report  on Form&nbsp;8-K filed on September&nbsp;3, 2008).</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">5.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Opinion of Ropes &#038; Gray LLP.</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">23.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Mayer Hoffman McCann P.C.</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">23.2</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Ropes &#038; Gray LLP (included in the opinion filed as Exhibit&nbsp;5.1).</DIV></TD>
  </TR>
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">24.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Powers of Attorney (included on the signature page in Part II).</DIV></TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  <!-- link2 "Item&nbsp;9. Undertakings." -->
  
  <DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;9. Undertakings.</B>
  </DIV>
  
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(a)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The undersigned Registrant hereby undertakes:</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="6%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(1)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>To file, during any period in which offers or sales are being
  made, a post-effective amendment to this Registration Statement:</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="10%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(i)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>To include any prospectus required by Section
  10(a)(3) of the Securities Act of 1933, as amended (the &#147;Securities
  Act&#148;);</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="10%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(ii)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>To reflect in the prospectus any facts or
  events arising after the effective date of the Registration Statement
  (or the most recent post-effective amendment thereof) which,
  individually or in the aggregate, represent a fundamental change in the
  information set forth in the Registration Statement. Notwithstanding
  the foregoing, any increase or decrease in volume of securities offered
  (if the total dollar value of securities offered would not exceed that
  which was registered) and any deviation from the low or high end of the
  estimated maximum offering range may be reflected in the form of a
  prospectus filed with the Commission pursuant to Rule 424(b) if, in the
  aggregate, the changes in volume and price represent no more than 20
  percent change in the maximum aggregate offering price set forth in the
  &#147;Calculation of Registration Fee&#148; table in the effective registration
  statement;</TD>
  </TR>
  
  </TABLE>
  </DIV>
  <P align="center" style="font-size: 10pt"><!-- Folio -->-3-<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  <DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="10%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(iii)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>To include any material information with
  respect to the plan of distribution not previously disclosed in the
  Registration Statement or any material change to such information in
  the Registration Statement;</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 6%"><I>provided, however</I>, that paragraphs (a)(1)(i) and (a)(1)(ii) above shall not apply if
  the information required to be included in a post-effective amendment by those
  paragraphs is contained in periodic reports filed with or furnished to the
  Commission by the Registrant pursuant to Section&nbsp;13 or 15(d) of the Exchange Act
  that are incorporated by reference in the Registration Statement.
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="6%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(2)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>That, for the purpose of determining any liability under the
  Securities Act, each such post-effective amendment shall be deemed to be a new
  registration statement relating to the securities offered therein, and the
  offering of such securities at that time shall be deemed to be the initial <I>bona
  fide </I>offering thereof.</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="6%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(3)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>To remove from registration by means of a post-effective
  amendment any of the securities being registered which remain unsold at the
  termination of the offering.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  
  <DIV style="margin-top: 6pt">
  <TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  <TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(b)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>The undersigned Registrant hereby undertakes that, for purposes of determining
  any liability under the Securities Act, each filing of the Registrant&#146;s annual report
  pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each
  filing of an employee benefit plan&#146;s annual report pursuant to Section 15(d) of the
  Exchange Act) that is incorporated by reference in the Registration Statement shall be
  deemed to be a new Registration Statement relating to the securities offered therein,
  and the offering of such securities at that time shall be deemed to be the initial <I>bona
  fide </I>offering thereof.</TD>
  </TR>
  
  <TR>
      <TD style="font-size: 6pt">&nbsp;</TD>
  </TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
      <TD width="2%" style="background: transparent">&nbsp;</TD>
      <TD width="3%" nowrap align="left">(c)</TD>
      <TD width="1%">&nbsp;</TD>
      <TD>Insofar as indemnification for liabilities arising under the Securities Act may
  be permitted to directors, officers and controlling persons of the Registrant pursuant
  to the foregoing provisions, or otherwise, the Registrant has been advised that in the
  opinion of the Commission such indemnification is against public policy as expressed in
  the Securities Act and is, therefore, unenforceable. In the event that a claim for
  indemnification against such liabilities (other than the payment by the Registrant of
  expenses incurred or paid by a director, officer or controlling person of the
  Registrant in the successful defense of any action, suit or proceeding) is asserted by
  such director, officer or controlling person in connection with the securities being
  registered, the Registrant will, unless in the opinion of its counsel the matter has
  been settled by controlling precedent, submit to a court of appropriate jurisdiction
  the question whether such indemnification by it is against public policy as expressed
  in the Securities Act and will be governed by the final adjudication of such issue.</TD>
  </TR>
  
  </TABLE>
  </DIV>
  <P align="center" style="font-size: 10pt"><!-- Folio -->-4-<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  
  <DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
  
  
  
  </TABLE>
  </DIV>
  <!-- link1 "SIGNATURES" -->
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>SIGNATURES</B>
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it
  has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
  has duly caused this Registration Statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the City of Milford, The Commonwealth of Massachusetts, on this 13
  day of March, 2009.
  </DIV>
  
  <TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
  <TR>
      <TD width="48%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="35%">&nbsp;</TD>
      <TD width="15%">&nbsp;</TD>
  </TR>
  <TR>
      <TD valign="top" align="left">&nbsp;</TD>
      <TD colspan="3" align="left"><FONT style="font-variant: SMALL-CAPS"><B>SeraCare Life Sciences, Inc.</B></FONT><BR>
  &nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD valign="top">By:&nbsp;&nbsp;</TD>
      <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ Susan L.N. Vogt
  &nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top">Name:&nbsp;&nbsp;</TD>
      <TD align="left">Susan L.N. Vogt&nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR><TR>
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top">Title:&nbsp;&nbsp;</TD>
      <TD align="left">President and Chief Executive Officer&nbsp;</TD>
      <TD>&nbsp;</TD>
  </TR>
  <TR>
      <TD colspan="5">&nbsp;</TD>
  </TR>
  </TABLE>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>POWER OF ATTORNEY</B>
  </DIV>
  
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each person whose signature appears below constitutes and appoints Susan L.N. Vogt and Gregory
  A. Gould, and each of them singly, his or her true and lawful attorney-in-fact and agent with full
  power of substitution and resubstitution, for him or her and in his or her name, place and stead,
  in any and all capacities, to sign any and all amendments (including post-effective amendments) to
  this Registration Statement on Form S-8 to be filed by SeraCare Life Sciences, Inc., and to file
  the same, with all exhibits thereto, and other documents in connection therewith, with the
  Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and
  authority to be done in and about the premises, as fully to all intents and purposes as he or she
  might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and
  agents, or their substitutes, may lawfully do or cause to be done by virtue hereof.
  </DIV>
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt">* * * *
  </DIV>
  
  
  <DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration
  Statement has been signed by the following persons in the capacities and on the dates indicated:
  </DIV>
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="40%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="40%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="14%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" style="border-bottom: 1px solid #000000">Signature</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="left" style="border-bottom: 1px solid #000000">Title</TD>
      <TD>&nbsp;</TD>
      <TD nowrap align="left" style="border-bottom: 1px solid #000000">Date</TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Susan L.N. Vogt</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Susan L.N. Vogt</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  President and Chief Executive Officer
  Director
  (Principal Executive Officer)
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Gregory A. Gould</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Gregory A. Gould</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  Chief Financial Officer, Treasurer and Secretary
  (Principal Financial and Accounting Officer)
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Eugene I. Davis</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Eugene I. Davis</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  Chairman
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Samuel D. Anderson</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Samuel D. Anderson</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  Director
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Sarah L. murphy</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Sarah L. Murphy</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  Director
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em"><!-- Blank Space -->
      <TD align="left">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
  </TR>
  <TR valign="bottom" style="padding-top: 1em">
      <TD align="left" nowrap valign="top"><FONT style="font-variant: SMALL-CAPS">/s/ Jill Tillman</FONT>
  <DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
  Jill Tillman</TD>
      <TD>&nbsp;</TD>
      <TD align="left">
  Director
  </TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">March 13, 2009</TD>
  </TR>
  <!-- End Table Body -->
  </TABLE>
  </DIV>
  
  
  <P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
  </DIV>
  
  <!-- PAGEBREAK -->
  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  
  <DIV style="font-family: 'Times New Roman',Times,serif">
  
  <!-- link1 "EXHIBIT INDEX" -->
  
  <DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>EXHIBIT INDEX</B>
  </DIV>
  
  
  <DIV align="center">
  <TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
  <!-- Begin Table Head -->
  <TR valign="bottom">
      <TD width="3%">&nbsp;</TD>
      <TD width="3%">&nbsp;</TD>
      <TD width="1%">&nbsp;</TD>
      <TD width="88%">&nbsp;</TD>
  </TR>
  <TR style="font-size: 8pt" valign="bottom">
      <TD nowrap align="left" colspan="2">Exhibit</TD>
  </TR>
  
  <!-- End Table Head -->
  <!-- Begin Table Body -->
  <TR valign="bottom"><!-- Blank Space -->
      <TD nowrap align="right" valign="top">&nbsp;</TD>
      <TD align="left"  valign="top">&nbsp;</TD>
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
  </TR>
  <TR valign="bottom">
      <TD align="left"  valign="top">4.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">2009 Equity Incentive Plan</DIV></TD>
  </TR>
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      <TD align="left"  valign="top">5.1</TD>
      <TD nowrap valign="top">&nbsp;</TD>
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      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Opinion of Ropes &#038; Gray LLP.</DIV></TD>
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      <TD align="left"  valign="top">23.1</TD>
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      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Mayer Hoffman McCann P.C.</DIV></TD>
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      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Ropes &#038; Gray LLP (included in the opinion filed as Exhibit&nbsp;5.1).</DIV></TD>
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      <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Powers of Attorney (included on the signature page in Part II).</DIV></TD>
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metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "b74641slsv8.htm", "description": "SERACARE LIFE SCIENCES, INC.", "secsgml_size_bytes": 47367}]
metadata_filer: {"company-data": {"conformed-name": "SERACARE LIFE SCIENCES INC", "cik": "0001156295", "assigned-sic": "2835", "irs-number": "330056054", "fiscal-year-end": "0930"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-157933", "film-number": "09680514"}, "business-address": {"street1": "37 BIRCH STREET", "city": "MILFORD", "state": "MA", "zip": "01757", "phone": "5082446400"}, "mail-address": {"street1": "37 BIRCH STREET", "city": "MILFORD", "state": "MA", "zip": "01757"}}
text: sv8
  As filed with the Securities and Exchange Commission on March 13, 2009
  Registration No. 333-
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT
  UNDER
  THE SECURITIES ACT OF 1933
  SeraCare Life Sciences, Inc.
  (Exact name of registrant as specified in its charter)
  Delaware
  (State or other jurisdiction
  of incorporation or organization)
  33-0056054
  (I.R.S. Employer
  Identification No.)
  37 Birch Street
  Milford, MA 01757
  (508) 244-6400
  (Address of principal executive offices, including zip code)
  2009 Equity Incentive Plan
  (Full title of the plans)
  Gregory A. Gould
  37 Birch Street
  Milford, MA 01757
  (508) 244-6400
  (Name, address and telephone number, including area code, of agent for service)
  Please send copies of all communications to:
  Hemmie Chang, Esq.
  Ropes & Gray LLP
  One International Place
  Boston, MA 02110
  617-951-7000
  617-951-7050 (facsimile)
  Indicate by check
  mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a
  smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer"
  and "smaller reporting company" in Rule 12b-2 of the Exchange Act. (Check one):
  Large accelerated filer
  o
  Accelerated filer
  o
  Non-accelerated filer
  þ
  (Do not check if a smaller reporting company)
  Smaller reporting company
  o
  CALCULATION OF REGISTRATION FEE
  Proposed
  Proposed
  Title of
  maximum
  maximum
  securities to be
  Amount to be
  offering
  aggregate
  Amount of
  registered
  registered (1)
  price per share (2)
  offering price (2)
  registration fee
  Common Stock, par value $0.001 per share
  1,500,000
  $
  0.52
  $
  780,000
  $
  30.65
  (1)
  This Registration Statement covers an aggregate of 1,500,000 shares of the Registrant's
  common stock, par value $0.001 per share (the "Common Stock"), that may be issued pursuant to
  awards granted under the equity plan identified above (the "Plan"). In addition, pursuant to
  Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act of 1933") this
  Registration Statement also covers such additional shares of Common Stock as may be issued
  pursuant to the antidilution provisions of the Plan to which this Registration Statement
  relates.
  (2)
  Estimated solely for the purposes of calculating the amount of registration fee. In
  accordance with Rule 457(h) and (c) of the Securities Act of 1933, as amended, the price shown
  is the average high and low selling prices of the common stock for March 9, 2009 as
  reported on the NASDAQ Capital Market.
  PART I
  INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
  The information required by Item 1 has been sent or given to employees as specified by Rule
  428(b)(1). Such documents are not being filed with the Securities and Exchange Commission (the
  "Commission") either as part of this Registration Statement or as prospectuses or prospectus
  supplements pursuant to Rule 424. Such documents and the documents incorporated by reference in
  this Registration Statement pursuant to Item 3 of Part II of this Form, taken together, constitute
  a prospectus that meets the requirements of Section 10(a) of the Securities Act.
  PART II
  INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
  Item 3. Incorporation of Documents by Reference.
  SeraCare Life Sciences, Inc. (the "Registrant") hereby incorporates the following documents
  herein by reference:
  (a)
  The Registrant's latest annual report on Form 10-K for the fiscal year ended
  September 30, 2008, filed with the Commission pursuant to the Securities Exchange Act
  of 1934, as amended (the "Exchange Act"), on December 8, 2008.
  (b)
  The Registrant's Quarterly Report for the quarter ended December 31, 2008 on
  Form 10-Q filed on February 17, 2009.
  (c)
  The Registrant's Current Reports on Form 8-K filed on December 8, 2008,
  December 22, 2008 and February 17, 2009.
  (d)
  The description of the Common Stock, $0.001 par value per share, contained in
  Item 1 of the Registrant's Registration Statement on Form 8-A, filed with the
  Commission pursuant to Section 12 of the Exchange Act on June 20, 2008.
  All documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and
  15(d) of the Exchange Act, prior to the filing of a post-effective amendment to this Registration
  Statement that indicates that all securities offered have been sold or which deregisters all
  securities then remaining unsold, shall be deemed to be incorporated herein by reference from the
  date of filing of such documents.
  Item 4. Description of Securities.
  Not applicable.
  Item 5. Interests of Named Experts and Counsel.
  Not applicable.
  Item 6. Indemnification of Directors and Officers.
  The Registrant is incorporated under the laws of the State of Delaware. Section 145 ("Section
  145") of the General Corporation Law of the State of Delaware, as the same exists or may hereafter
  be amended (the "General Corporation Law"), inter alia, provides that a Delaware corporation may
  indemnify any persons who were, are or are threatened to be made, parties to any threatened,
  pending or completed action, suit or proceeding, whether civil, criminal, administrative or
  investigative (other than an action by or in the right of such corporation), by reason of the fact
  that such person is or was an officer, director, employee or agent of such corporation, or is or
  was serving at the request of such corporation as a director, officer, employee or agent of another
  corporation or enterprise. The indemnity may include expenses (including attorneys' fees),
  judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in
  connection with such action, suit or proceeding, provided such person acted in good faith and in a
  manner he reasonably believed to be in or not opposed to the corporation's best interests and, with
  respect to any criminal action or proceeding, had no reasonable cause to believe that his conduct
  was illegal. In addition, the statutes of Delaware contain provisions to the general effect that
  any director shall in the performance of his duties be fully protected in relying in good faith
  upon the books of account or records of the corporation or statements prepared by any official of
  the corporation.
  The Registrant's certificate of incorporation provides that the Registrant shall, to the
  fullest extent permitted under and in accordance with the laws of the State of Delaware, indemnify
  any person who was or is a party or is threatened to be made a party to any threatened, pending or
  completed action, suit or proceeding by reason of the fact that he is or was, or has agreed to
  become, a director or officer of the Registrant. The indemnification provided for in the
  Registrant's certificate of incorporation is expressly not exclusive of any provisions with respect
  thereto in the Registrant's Bylaws or any other contract or agreement between the Registrant and
  any officer, director, employee or agent of the Registrant.
  Section 145 further authorizes a corporation to purchase and maintain insurance on behalf of
  any person who is or was a director, officer, employee or agent of the corporation, or is or was
  serving at the request of the corporation as a director, officer, employee or agent of another
  corporation or enterprise, against any liability asserted against him and incurred by him in any
  such capacity, arising out of his status as such, whether or not the corporation would otherwise
  have the power to indemnify him under Section 145.
  We currently have directors' and officers' liability insurance to provide our directors and
  officers with insurance coverage for losses arising from claims based on breaches of duty,
  negligence, errors and other wrongful acts.
  Section 102(b)(7) of the General Corporation Law of the State of Delaware provides that a
  corporation may eliminate or limit the personal liability of a director to the corporation or its
  stockholders for monetary damages for breach of fiduciary duty as a director, provided that such
  provision shall not eliminate or limit the liability of a director (i) for any breach of the
  director's duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not
  in good faith or which involve intentional misconduct or a knowing violation of law, (iii) under
  Section 174 of the General Corporation Law of the State of Delaware, or (iv) for any transaction
  from which the director derived an improper personal benefit. No such provision shall eliminate or
  limit the liability of a director for any act or omission occurring prior to the date when such
  provision becomes effective.
  The Registrant's certificate of incorporation provides that the liability of the directors for
  monetary damages shall be eliminated to the fullest extent under applicable law. If the General
  Corporation Law is amended to authorize corporate action further eliminating or limiting the
  personal liability of directors, then the liability of a director of the corporation shall be eliminated to the fullest extent permitted by the General
  Corporation Law, as so amended.
  -2-
  Item 7. Exemption From Registration Claimed.
  Not applicable.
  Item 8. Exhibits.
  Exhibit
  4.1
  2009 Equity Incentive Plan.
  4.2
  Certificate of Incorporation (previously filed as Exhibit 3.1 to the
  Registrant's Registration Statement on Form 8-A filed on May 17, 2007).
  4.3
  Amended and Restated By-laws (previously filed as Exhibit 3.1 to the
  Registrant's Current Report  on Form 8-K filed on September 3, 2008).
  5.1
  Opinion of Ropes & Gray LLP.
  23.1
  Consent of Mayer Hoffman McCann P.C.
  23.2
  Consent of Ropes & Gray LLP (included in the opinion filed as Exhibit 5.1).
  24.1
  Powers of Attorney (included on the signature page in Part II).
  Item 9. Undertakings.
  (a)
  The undersigned Registrant hereby undertakes:
  (1)
  To file, during any period in which offers or sales are being
  made, a post-effective amendment to this Registration Statement:
  (i)
  To include any prospectus required by Section
  10(a)(3) of the Securities Act of 1933, as amended (the "Securities
  Act");
  (ii)
  To reflect in the prospectus any facts or
  events arising after the effective date of the Registration Statement
  (or the most recent post-effective amendment thereof) which,
  individually or in the aggregate, represent a fundamental change in the
  information set forth in the Registration Statement. Notwithstanding
  the foregoing, any increase or decrease in volume of securities offered
  (if the total dollar value of securities offered would not exceed that
  which was registered) and any deviation from the low or high end of the
  estimated maximum offering range may be reflected in the form of a
  prospectus filed with the Commission pursuant to Rule 424(b) if, in the
  aggregate, the changes in volume and price represent no more than 20
  percent change in the maximum aggregate offering price set forth in the
  "Calculation of Registration Fee" table in the effective registration
  statement;
  -3-
  (iii)
  To include any material information with
  respect to the plan of distribution not previously disclosed in the
  Registration Statement or any material change to such information in
  the Registration Statement;
  provided, however
  , that paragraphs (a)(1)(i) and (a)(1)(ii) above shall not apply if
  the information required to be included in a post-effective amendment by those
  paragraphs is contained in periodic reports filed with or furnished to the
  Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange Act
  that are incorporated by reference in the Registration Statement.
  (2)
  That, for the purpose of determining any liability under the
  Securities Act, each such post-effective amendment shall be deemed to be a new
  registration statement relating to the securities offered therein, and the
  offering of such securities at that time shall be deemed to be the initial
  bona
  fide
  offering thereof.
  (3)
  To remove from registration by means of a post-effective
  amendment any of the securities being registered which remain unsold at the
  termination of the offering.
  (b)
  The undersigned Registrant hereby undertakes that, for purposes of determining
  any liability under the Securities Act, each filing of the Registrant's annual report
  pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each
  filing of an employee benefit plan's annual report pursuant to Section 15(d) of the
  Exchange Act) that is incorporated by reference in the Registration Statement shall be
  deemed to be a new Registration Statement relating to the securities offered therein,
  and the offering of such securities at that time shall be deemed to be the initial
  bona
  fide
  offering thereof.
  (c)
  Insofar as indemnification for liabilities arising under the Securities Act may
  be permitted to directors, officers and controlling persons of the Registrant pursuant
  to the foregoing provisions, or otherwise, the Registrant has been advised that in the
  opinion of the Commission such indemnification is against public policy as expressed in
  the Securities Act and is, therefore, unenforceable. In the event that a claim for
  indemnification against such liabilities (other than the payment by the Registrant of
  expenses incurred or paid by a director, officer or controlling person of the
  Registrant in the successful defense of any action, suit or proceeding) is asserted by
  such director, officer or controlling person in connection with the securities being
  registered, the Registrant will, unless in the opinion of its counsel the matter has
  been settled by controlling precedent, submit to a court of appropriate jurisdiction
  the question whether such indemnification by it is against public policy as expressed
  in the Securities Act and will be governed by the final adjudication of such issue.
  -4-
  SIGNATURES
  Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it
  has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
  has duly caused this Registration Statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the City of Milford, The Commonwealth of Massachusetts, on this 13
  day of March, 2009.
  SeraCare Life Sciences, Inc.
  By:
  /s/ Susan L.N. Vogt
  Name:
  Susan L.N. Vogt
  Title:
  President and Chief Executive Officer
  POWER OF ATTORNEY
  Each person whose signature appears below constitutes and appoints Susan L.N. Vogt and Gregory
  A. Gould, and each of them singly, his or her true and lawful attorney-in-fact and agent with full
  power of substitution and resubstitution, for him or her and in his or her name, place and stead,
  in any and all capacities, to sign any and all amendments (including post-effective amendments) to
  this Registration Statement on Form S-8 to be filed by SeraCare Life Sciences, Inc., and to file
  the same, with all exhibits thereto, and other documents in connection therewith, with the
  Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and
  authority to be done in and about the premises, as fully to all intents and purposes as he or she
  might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and
  agents, or their substitutes, may lawfully do or cause to be done by virtue hereof.
  * * * *
  Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration
  Statement has been signed by the following persons in the capacities and on the dates indicated:
  Signature
  Title
  Date
  /s/ Susan L.N. Vogt
  Susan L.N. Vogt
  President and Chief Executive Officer
  Director
  (Principal Executive Officer)
  March 13, 2009
  /s/ Gregory A. Gould
  Gregory A. Gould
  Chief Financial Officer, Treasurer and Secretary
  (Principal Financial and Accounting Officer)
  March 13, 2009
  /s/ Eugene I. Davis
  Eugene I. Davis
  Chairman
  March 13, 2009
  /s/ Samuel D. Anderson
  Samuel D. Anderson
  Director
  March 13, 2009
  /s/ Sarah L. murphy
  Sarah L. Murphy
  Director
  March 13, 2009
  /s/ Jill Tillman
  Jill Tillman
  Director
  March 13, 2009
  EXHIBIT INDEX
  Exhibit
  4.1
  2009 Equity Incentive Plan
  5.1
  Opinion of Ropes & Gray LLP.
  23.1
  Consent of Mayer Hoffman McCann P.C.
  23.2
  Consent of Ropes & Gray LLP (included in the opinion filed as Exhibit 5.1).
  24.1
  Powers of Attorney (included on the signature page in Part II).