Datasets:
lchen915
/
litscrape-af2af3-k5

Dataset card Data Studio Files
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1
litscrape_id
string
source_row_index
int64
binder_id
string
source_publication
string
target
string
label
int64
binding_affinity_nm
float64
target_sequence
string
binder_sequence
string
af2_model_name
string
af3_model_name
string
af2_complex_plddt
float64
af2_ptm
float64
af2_iptm
float64
af2_pae
float64
af2_ipae
float64
af2_min_ipae
float64
af3_ptm
float64
af3_iptm
float64
af3_chain_A_plddt
float64
af3_chain_A_pae
float64
af3_chain_A_ptm
float64
af3_chain_A_iptm
float64
af3_chain_B_plddt
float64
af3_chain_B_pae
float64
af3_chain_B_ptm
float64
af3_chain_B_iptm
float64
af3_iptm_A_B
float64
status
string
error
float64
af3k5_k_samples
int64
af3k5_ptm_mean
float64
af3k5_ptm_std
float64
af3k5_ptm_min
float64
af3k5_ptm_max
float64
af3k5_iptm_mean
float64
af3k5_iptm_std
float64
af3k5_iptm_min
float64
af3k5_iptm_max
float64
af3k5_binder_plddt_mean
float64
af3k5_binder_plddt_std
float64
af3k5_binder_plddt_min
float64
af3k5_binder_plddt_max
float64
af3k5_ranking_score_mean
float64
af3k5_ranking_score_std
float64
af3k5_ranking_score_min
float64
af3k5_ranking_score_max
float64
af3k5_ptm_best
float64
af3k5_iptm_best
float64
af3k5_binder_plddt_best
float64
af3k5_ranking_score_best
float64
af3k5_has_clash_frac
float64
litscrape_000200
200
EEHEE_12482_000000025_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
TVIVIIVIFYNGDFIFIDVDVDDSPRDKKKAQEIVEKASEHAHKLGGKLTVVIFDGDKVKTQRYK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4762
0.3927
0.0838
0.6531
0.826
0.5351
0.32259
0.084059
52.055694
15.817391
0.404951
0.084059
55.523237
5.989015
0.548565
0.084059
0.084059
ok
null
5
0.303821
0.009302
0.287412
0.314121
0.098834
0.005928
0.094097
0.110487
57.284949
4.283218
50.334674
61.018849
0.198452
0.012753
0.177077
0.216794
0.301178
0.094097
54.204602
0.216794
0
litscrape_000201
201
EHEE_11067_000000026_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
VLAYFVEYKLKGNSPEAQKKASDVAKRISTDLTKKAKSWGGDVEYDWLWFTNGDTVIVIILVFVI
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5749
0.3793
0.1305
0.5703
0.7454
0.4354
0.378567
0.24093
54.094733
15.163478
0.404786
0.24093
67.285337
4.738963
0.60902
0.24093
0.24093
ok
null
5
0.375577
0.004057
0.370606
0.380307
0.213678
0.01283
0.202939
0.238851
68.316313
0.189907
68.085164
68.629505
0.322412
0.013401
0.306646
0.34596
0.380307
0.238851
68.629505
0.34596
0
litscrape_000202
202
csplice_r1_HEEH_25006_000000001_0001_0001_43_52_H____ems_3hM_3100_0001_0002_0001_0001_4_41_HHH_34_26465_29_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
VLELVARILIKLALELNDEELLELAAKALLEALKKKGIPPEEARKIVEKFLRELGVPPEVIEKAK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6379
0.3107
0.0909
0.6093
0.8122
0.5339
0.362504
0.112354
48.120281
17.487039
0.336228
0.112354
70.832887
2.686403
0.761279
0.112354
0.112354
ok
null
5
0.363349
0.002357
0.360638
0.367357
0.143619
0.031703
0.108948
0.181714
72.886956
0.30905
72.397988
73.208398
0.244215
0.025277
0.215457
0.281776
0.36183
0.181714
73.133165
0.281776
0
litscrape_000203
203
csplice_r1_a2de759c170706188c6e693fd8ea43cc_0001_000000001_0001_0001_38_47_H____ems_p1_14H_GBL_16H_GBL_14H_0120_0001_0001_0001_0001_0002_0001_0001_18_49_HHH_28_09256_27_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
VLGTAARIIAESAVELGNVELALKALEALAKAEKDPRLEELVRRAEELLRRGDPEKARELLKKAA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6636
0.37
0.085
0.6115
0.8211
0.5219
0.361917
0.124884
47.718021
17.806528
0.336333
0.124884
72.809435
2.974285
0.727482
0.124884
0.124884
ok
null
5
0.350798
0.00435
0.347401
0.359335
0.130536
0.017672
0.108265
0.152508
74.916499
0.325435
74.354761
75.337767
0.264243
0.010551
0.24911
0.27802
0.349032
0.152508
74.987263
0.27802
0
litscrape_000204
204
ems_ferrC_1476_000000001_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
VTVLFINVDPSEAKTVAKLANVKSFEVETFGDVIHVEVHGVSPEQLKKAIKLVGAAVLVLG
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4501
0.3986
0.0756
0.6873
0.8469
0.6016
0.382009
0.097327
61.930804
13.394787
0.479026
0.097327
58.389661
6.800094
0.455087
0.097327
0.097327
ok
null
5
0.320035
0.012742
0.307525
0.343173
0.094938
0.006364
0.085079
0.104576
60.045524
0.904571
58.869715
61.384821
0.246992
0.009065
0.235084
0.262309
0.343173
0.09762
58.869715
0.262309
0
litscrape_000205
205
ems_ferrM_1564_000000000_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
WFVVITVDSESLADVFKKLGAVVFTWGDKVFVFVINVSPEQVKKVASEANAEFRIFP
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5146
0.421
0.0628
0.6905
0.8716
0.5942
0.277495
0.06356
50.688751
17.768079
0.338615
0.06356
58.338953
5.124856
0.527714
0.06356
0.06356
ok
null
5
0.271515
0.0033
0.267746
0.27687
0.095918
0.00738
0.08789
0.105215
60.555568
0.368501
60.034643
60.973448
0.221294
0.005836
0.211574
0.228236
0.27687
0.103897
60.92327
0.228236
0
litscrape_000206
206
ems_ferrM_3544_0002_000000011_0001
Cao et al VirB8
VirB8
0
null
ANPYISVANIMLQNYVKQREKYNYDTLKEQFTFIKNASTSIVYMQFANFMNIDNSLSPVIRYQKLYRRSINIISINNINNNEATVTFESLAQNNTGEILENMLWEAKIGFIMDSISTNMPFHFIVTSYKLKLLRNKNQ
WVVVFVRNVDVRLVQKAAKIAGAVEVFQIGHLVAIIIEDESHARIVEELVKKEAQAEVTVFTV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6226
0.3939
0.0806
0.6332
0.8413
0.4988
0.330536
0.074374
52.630347
17.297947
0.337408
0.074374
70.420374
3.065475
0.734304
0.074374
0.074374
ok
null
5
0.340789
0.002566
0.336127
0.343262
0.121603
0.005062
0.112668
0.128395
72.34262
0.320184
71.843148
72.674779
0.256982
0.007573
0.244424
0.268259
0.34194
0.122352
72.674779
0.268259
0
litscrape_000207
207
IL7RA_02
PPIFlow manual curation
IL7Ra
1
0.316
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGALKPPTPAEQLKDIAAAIKEAAAKGELIEMTQLLSFTLLVASKIFGLDPELAAEMLRLLYLAAISENPEPIVKKAIELLNKLAEEAAKVDPETAAILKEAAERLAENPENVEPVLAELGIALAEHLAKHPKVKEMGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7666
0.4426
0.1367
0.5808
0.847
0.4888
0.445296
0.116661
50.52904
18.908732
0.362588
0.116661
77.110847
6.275963
0.819705
0.116661
0.116661
ok
null
5
0.447149
0.003709
0.441312
0.452275
0.115375
0.005257
0.108019
0.123187
77.641144
0.175433
77.351953
77.825284
0.21773
0.006182
0.21182
0.229004
0.452275
0.123187
77.729438
0.229004
0
litscrape_000208
208
IL7RA_17
PPIFlow manual curation
IL7Ra
1
116
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGDELFKEVNKEMKELLEKGKPELAEIIEEAMFLLDVSKKLAKKAKIVLETKDEELKKDLLEALKEFVERLKKFVEKVKKNIEELSEATAKLIALMAKELKKTAKEIEKVDPELAKEIKKLAEELEAILKSNPKHKKVVEELEGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7859
0.4589
0.1449
0.5604
0.8351
0.4697
0.467108
0.137189
48.330326
19.41722
0.360052
0.137189
77.450356
6.073341
0.821639
0.137189
0.137189
ok
null
5
0.458924
0.004829
0.449958
0.463945
0.122472
0.007171
0.109304
0.131193
77.364978
0.162566
77.157516
77.542458
0.213919
0.009578
0.198502
0.228642
0.463945
0.131193
77.538973
0.228642
0
litscrape_000209
209
IL7RA_15
PPIFlow manual curation
IL7Ra
1
60.5
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGDITEEELKKAEIEVAAILIAITIVVLIFAGMYTKELVEKLLSTPVEEVKKLLEELEDLIEEALEKIYSRKDEKIGPIKEEILAKLKEAIAIAKALKPKSGELATLVAERLKAAAEVVKKMPDDATITEALSKAIDAIRGHGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7484
0.4457
0.1397
0.5885
0.8512
0.494
0.461346
0.120303
45.229101
20.212011
0.332105
0.120303
77.371451
6.277352
0.835192
0.120303
0.120303
ok
null
5
0.462692
0.00522
0.457327
0.472677
0.133768
0.014788
0.115787
0.160622
77.111782
0.311264
76.777602
77.66398
0.237017
0.012405
0.219306
0.258244
0.472677
0.160622
77.66398
0.258244
0
litscrape_000210
210
IL7RA_28
PPIFlow manual curation
IL7Ra
1
115
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGDLIEEAKKIEDETLKKIVEIMLTIDPSLAELPEEEKKLIARAFVYLLYRHEEKLKYLDDKEKLLEILEELLKDAKNGAKTSLDEKVKKALDKLAEILEKLIKLAKEGDTSYFKKIVNTIEEGEKQIQELLKSASGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7094
0.4066
0.1146
0.6262
0.8822
0.5419
0.441915
0.12785
44.167507
20.253421
0.329532
0.12785
72.547045
7.493083
0.782601
0.12785
0.12785
ok
null
5
0.445931
0.003546
0.439606
0.449454
0.133512
0.0057
0.122916
0.138516
73.088512
0.224281
72.831885
73.501055
0.22121
0.006203
0.209177
0.226404
0.449051
0.138507
72.996305
0.226404
0
litscrape_000211
211
IL7RA_08
PPIFlow manual curation
IL7Ra
1
88.5
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGDNITKEEFDEEIIKKLKELAEGKLEFENVDEAYAFLALVARIIAKKTGKEEEIGKILSRAYIGMKYAEDESTLEKALEIAKEFAEEVEKMRKEGIFNAEYIVLAFAAYFIAKFLEKKGVKEAAEIRERIKEAVKEGAEKVIKIIKEGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7752
0.4516
0.1281
0.589
0.8803
0.5404
0.464507
0.111614
51.936557
17.954777
0.381734
0.111614
77.886956
6.205477
0.842743
0.111614
0.111614
ok
null
5
0.459309
0.001881
0.457418
0.462659
0.101411
0.003788
0.096826
0.107604
77.67346
0.078785
77.593598
77.781192
0.203739
0.003677
0.199463
0.210471
0.462659
0.107604
77.621559
0.210471
0
litscrape_000212
212
IL7RA_14
PPIFlow manual curation
IL7Ra
1
69.8
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGDWRAEQLARLAELEAELAKLMKEADSKEVMEVLEKAHALLSLAQSLLEEDEDVSLSLFIYSILVLSKWPELKKEIYEEVAKKSPELLKKLEEIEKLIEEQKKNPENLEIVKELKKLLKELRADEEAVRALLEVLLEHLERLLAEARKLLGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7918
0.4838
0.1591
0.5477
0.83
0.413
0.507736
0.178593
47.570024
18.700259
0.370771
0.178593
79.255887
5.348854
0.849412
0.178593
0.178593
ok
null
5
0.498192
0.004056
0.491127
0.502161
0.158501
0.008589
0.143701
0.16647
79.203936
0.143979
79.038244
79.434829
0.248692
0.009372
0.232417
0.258333
0.502161
0.16647
79.434829
0.258333
0
litscrape_000213
213
IL7RA_12
PPIFlow manual curation
IL7Ra
1
86.5
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGEELLKELAEEIKRLLEDTEKLEEKLKAQGKPEEGKEAARRLLISFSLRMINRYLQKKPELKEIAKLIGKAILLLDEGKLEEAIKELEKAVELLKKLEGLEKRFGEIVELIAKILKAELEGNEKEAEKLYKKLKELLEKLAEELEKGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7607
0.4439
0.1253
0.5918
0.8771
0.5613
0.467649
0.122363
46.865948
19.745539
0.348134
0.122363
77.729912
6.062044
0.834434
0.122363
0.122363
ok
null
5
0.471593
0.001893
0.46994
0.475223
0.128137
0.004369
0.124498
0.136687
77.864778
0.105752
77.727668
78.045622
0.215717
0.005607
0.21172
0.226616
0.475223
0.136687
78.045622
0.226616
0
litscrape_000214
214
IL7RA_06
PPIFlow manual curation
IL7Ra
1
43.5
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGKEKELEEIDKLVEEVIELMEKVAKALGISEERKEEIEKEIKEKGAEEVFVELAESGPLEEALYAAALALKETKNLPIEERLKKIARIMAAISSYLEYIIENKGEEIPNLELLKELLELTNELLDKIQELEKKGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7231
0.4235
0.1343
0.6023
0.8493
0.5273
0.449263
0.133848
50.249495
18.485211
0.396958
0.133848
75.616865
6.722525
0.793547
0.133848
0.133848
ok
null
5
0.438959
0.006433
0.427143
0.446733
0.115896
0.010914
0.095971
0.12912
75.731605
0.204927
75.519639
76.065039
0.20731
0.011755
0.186701
0.221461
0.446733
0.12912
75.869028
0.221461
0
litscrape_000215
215
IL7RA_04
PPIFlow manual curation
IL7Ra
1
17.3
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGKIKISEELMASISVMIGIIAQELREAGKEVDPELAKKLEKLAEEMEKLMEEIGKLMQDPNAKEEEIKEKVKKLVKVLEEAAKLAKELGKPELAEAIKELIKIIKEVVEDPSKQEEALKRVEEIINKIQDEIIKKRGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7253
0.4323
0.1391
0.5882
0.8398
0.4489
0.474902
0.180299
55.200531
16.989142
0.409762
0.180299
75.147506
6.855666
0.792581
0.180299
0.180299
ok
null
5
0.488168
0.003309
0.482236
0.491584
0.21006
0.007128
0.198486
0.219383
75.934307
0.192028
75.607056
76.09619
0.29711
0.006139
0.286664
0.302498
0.488824
0.207703
76.09619
0.302498
0
litscrape_000216
216
IL7RA_30
PPIFlow manual curation
IL7Ra
1
97.4
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGLEEVAEEVKKLIEEIIKLLEELLSKLEIPEEDLAELEEMLKKKSPEEVFVETAEGGPIGVTILAAIEALKSVLKLPVEEFLEKAARFMAALSNYFEERKEEIVKKSGNEELVKKIIEKAEKALDLIQSIKLAGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7592
0.4231
0.1163
0.6067
0.8685
0.6036
0.432533
0.104035
53.884699
17.971764
0.386774
0.104035
75.896648
7.129597
0.802948
0.104035
0.104035
ok
null
5
0.437972
0.00252
0.433023
0.439885
0.112394
0.004715
0.103114
0.115524
76.390541
0.063863
76.327115
76.479533
0.205752
0.004121
0.199355
0.210308
0.439885
0.11509
76.456038
0.210308
0
litscrape_000217
217
IL7RA_07
PPIFlow manual curation
IL7Ra
1
44.1
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGMSEEIKEKIDKLKAEGNEDEIIKLTYSILSLLVGLFEDVGAEAVVKGLYDDLFFGDNKEEAEEVIKEFLGLVENAAYGIKLIFPEEAETMEEIVKLAKEAVEYLKEGKVEEAVKKLNEIYELLLEPLKKLGELLEKKLSGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7046
0.4208
0.1245
0.606
0.8589
0.5341
0.452358
0.127694
48.169549
18.813555
0.378809
0.127694
76.057938
6.860739
0.790888
0.127694
0.127694
ok
null
5
0.444987
0.00239
0.441439
0.448941
0.116933
0.004806
0.111975
0.125816
76.068607
0.227904
75.695615
76.321884
0.208815
0.003456
0.203291
0.21304
0.448941
0.125816
76.279993
0.21304
0
litscrape_000218
218
IL7RA_27
PPIFlow manual curation
IL7Ra
1
17.7
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGSGPTEEEYLEELLKEYEELKKKFEENPESMTLDDIVTLSAIARFLLSKGKKEEAMEVLAYAVKMAVAQGKYRTALALAAEIAKVAGDEELAKKIEEVFEKIETLDKETAKKLAAKALKEAAKALKKKGFEKTAKILKEAAKELEKGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.757
0.4504
0.1392
0.5812
0.8565
0.4659
0.46652
0.122945
45.99067
19.901927
0.33976
0.122945
77.555371
6.31761
0.828924
0.122945
0.122945
ok
null
5
0.462384
0.007465
0.452001
0.469138
0.120098
0.011042
0.105712
0.131689
77.187699
0.31033
76.782484
77.536651
0.228833
0.015494
0.212031
0.254691
0.468922
0.131689
77.536651
0.254691
0
litscrape_000219
219
IL7RA_29
PPIFlow manual curation
IL7Ra
1
112
DDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEI
MSGSGPTLEEYLEELKKEYEALKKKFAEDPASMTDDDIVTLSAIARALLSEGKKEEAMLVLADAAAMAAAQGKYRTLLQLVAALAEAAGDKELAEEIKKAFEEAETLSPEEAAKLAAKMVEKAAKALKEKGYEEAAKRLKEIAKRLKAGSGSHHWGSTHHHHHH
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7542
0.4453
0.1414
0.5804
0.852
0.4843
0.468472
0.126353
51.401477
17.945748
0.395067
0.126353
78.397072
6.051883
0.827886
0.126353
0.126353
ok
null
5
0.45918
0.003981
0.453394
0.465645
0.112814
0.008204
0.097844
0.122285
78.19952
0.259758
77.740945
78.539359
0.221532
0.005705
0.21062
0.227292
0.458454
0.112209
78.172909
0.227292
0
litscrape_000220
220
DerF7_b4
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
MEAIKLYYELALKVFLEKNVPDEEISRYLLMDVIGHWRNSPDFEKLVEMVKELLKENGVKVVEPVKYTREEERKYWKIHSLALKKLQERLGLSPREIQERMAEIMREAMESEDPKKVFEERKEEVEEYLVLFFELEVEAMKKVLNI
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7145
0.3888
0.1157
0.5999
0.8822
0.5899
0.387417
0.082539
42.824333
20.381235
0.258921
0.082539
68.620372
5.639641
0.709497
0.082539
0.082539
ok
null
5
0.395955
0.002396
0.391701
0.398548
0.09035
0.005783
0.079705
0.095572
68.933892
0.387527
68.162416
69.177784
0.176325
0.005049
0.166958
0.181021
0.398548
0.095572
69.177784
0.181021
0
litscrape_000221
221
DerF7_b6
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
MPTKEEVRELLEGYYREAVADPALWQGVVDGTLAREWAREILEKFGAASTPMSENMIEWLAMVLREAFKHMHNAETFGNRATDQSPEEFVEEQLDKLSEWLVKLIADPESVFK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7557
0.4039
0.121
0.6001
0.8529
0.4947
0.384343
0.085798
42.178025
20.801204
0.240483
0.085798
74.408553
4.37929
0.829009
0.085798
0.085798
ok
null
5
0.40004
0.003337
0.393627
0.402332
0.109863
0.004348
0.101736
0.113456
74.553437
0.388745
73.886138
75.066582
0.189258
0.007544
0.177913
0.199355
0.402227
0.112229
74.680806
0.199355
0
litscrape_000222
222
DerF7_b11
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
MTPLTFDDFIEEVKRAKEYIDTMPGEQQKKVVEFLRSTLYNIIWHPNHNDEEVHKVAKAIHFGKWTLDEEYAIEVLVKAIEKMIERGESGFEGFSKEELRKVAELLVEALKEITKIQPEGGRVKTDEQARKILEVFVEFVEKVEEIRE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8248
0.4639
0.133
0.5405
0.854
0.5057
0.444334
0.105064
41.167958
21.61512
0.218905
0.105064
75.589944
4.002823
0.833976
0.105064
0.105064
ok
null
5
0.450848
0.002829
0.446485
0.453379
0.116037
0.00436
0.110036
0.120997
76.079053
0.080373
75.946853
76.147127
0.201895
0.007178
0.190407
0.209202
0.453013
0.120997
76.137591
0.209202
0
litscrape_000223
223
DerF7_b5
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
SKDELADELLKKWWKAHLWAMKKLWDSKDPRLQELRERIQIVGGYVFNAGSKPPEERNYEEFKKYAEEFVELLEEVGELVEMSEEEKKLIEEIKEKLPEL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8044
0.4371
0.1282
0.5786
0.8227
0.4556
0.372163
0.08848
41.139392
21.383365
0.225059
0.08848
75.947814
2.387191
0.848284
0.08848
0.08848
ok
null
5
0.390138
0.002291
0.385924
0.392497
0.113598
0.003532
0.10688
0.116824
76.841972
0.221684
76.565151
77.043506
0.191541
0.004992
0.185472
0.198256
0.39181
0.116084
77.021442
0.198256
0
litscrape_000224
224
DerF7_b7
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
SLEELIAIPVAYLEKVDPELAKEFRAEALFYWPAMNGNWHLWRHSMKAYLRTNLHEDPELLEEALALLDEAYESL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6815
0.4654
0.1081
0.6331
0.824
0.5164
0.318245
0.088404
43.893009
19.965437
0.279834
0.088404
72.17709
2.686734
0.795381
0.088404
0.088404
ok
null
5
0.327124
0.003226
0.321698
0.331512
0.097947
0.004196
0.090969
0.103718
74.034737
0.177678
73.802347
74.319629
0.168137
0.010745
0.15003
0.176952
0.331512
0.103718
74.319629
0.176952
0
litscrape_000225
225
DerF7_b8
BindCraft
DerF7
0
null
DPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGILDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
TSEWSLEKFEEWTERYHGDSWSEEERKKAKEMIEEIAKLSMEEFMEFHTKVNSTIKPDPSISRKEQDFLDDKIYIDKGIEYFKSK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6557
0.4638
0.1094
0.6487
0.8454
0.5305
0.29563
0.075348
41.881773
20.880979
0.240147
0.075348
61.882633
6.315114
0.668403
0.075348
0.075348
ok
null
5
0.301229
0.002797
0.295793
0.303537
0.081164
0.003029
0.075269
0.083767
62.177636
0.381729
61.762659
62.776863
0.14048
0.00483
0.133609
0.148703
0.301474
0.081595
61.986047
0.148703
0
litscrape_000226
226
bcov_r3_ems_p1_15H_GBL_16H_GABBL_16H_0035_0001_0001_0002_000000044_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
AAENLLEWLLKYARKLGDKKAQKIVKTALKATRDGILSEEEAEEIASDIAAELLF
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6934
0.4023
0.0769
0.7031
0.8744
0.6423
0.258814
0.077558
39.893695
21.62679
0.251534
0.077558
71.357789
2.444018
0.718114
0.077558
0.077558
ok
null
5
0.286836
0.005327
0.278099
0.293102
0.158085
0.047357
0.068319
0.205293
74.665687
0.85319
73.006252
75.314093
0.195125
0.03886
0.124388
0.241
0.293102
0.205293
75.314093
0.241
0
litscrape_000227
227
IL7Ra_binder_design_66
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
AKEEVDKLVEEVRELAKEVESKKEELEAYAEILRVQAYELIEEGKEEEAKRVAEQGAKRAKEVAEEALKE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7559
0.3926
0.1038
0.6417
0.842
0.5143
0.309728
0.086754
38.625554
21.448253
0.281117
0.086754
75.128328
2.218155
0.802272
0.086754
0.086754
ok
null
5
0.322932
0.0065
0.311425
0.32914
0.110595
0.014851
0.087555
0.129325
76.114699
0.166565
75.854464
76.371106
0.162188
0.017568
0.132329
0.176892
0.32914
0.129325
76.371106
0.176892
0
litscrape_000228
228
IL7Ra_binder_design_18
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
AVEVAREAVEVAEEAAKKDPRLKPALEHVRKALEAVEAGDDEEAKKHLLEAAEVIAEVNPELGEALKKRIEEEEDLEKRAWLLRVALLTLLEQG
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8567
0.404
0.1211
0.581
0.8278
0.5035
0.363802
0.110763
37.241254
22.313521
0.254236
0.110763
78.467479
2.819428
0.837764
0.110763
0.110763
ok
null
5
0.364572
0.007841
0.349848
0.372356
0.101225
0.018771
0.070938
0.12731
78.768163
0.660296
78.099232
79.95528
0.166438
0.012765
0.1424
0.175758
0.369551
0.12731
78.944587
0.175758
0
litscrape_000229
229
longxing_Grafting2_ems_3hC_306_0002_0016_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDEEAEEAKKLVDKASKLNPTNRVIAQAIKADLTDAQRNKDKEDLRLAVRKVRLAYKHAK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5605
0.4641
0.1534
0.6704
0.8
0.5601
0.301843
0.09638
43.209616
19.580199
0.346868
0.09638
66.548469
3.367475
0.666109
0.09638
0.09638
ok
null
5
0.284101
0.006913
0.277173
0.295723
0.088377
0.011696
0.068489
0.102629
67.064942
0.285595
66.709552
67.483385
0.140565
0.014274
0.113936
0.15458
0.277173
0.091817
66.709552
0.15458
0
litscrape_000230
230
longxing_Grafting2_ems_3hC_306_0001_0002_0009_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDEEAEEAKKLVDKVSKTNPEARMAAQRIKDELTKAQRNKDKDDLRLAVLKVRLALNHAR
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4935
0.4309
0.0895
0.7361
0.8604
0.6145
0.291499
0.104605
49.428264
18.825444
0.338474
0.104605
63.295213
3.949012
0.597511
0.104605
0.104605
ok
null
5
0.295812
0.005736
0.285653
0.302501
0.114638
0.016384
0.08277
0.1272
67.819239
0.499715
66.91127
68.429533
0.170241
0.01195
0.146479
0.177452
0.296184
0.120595
67.797317
0.177452
0
litscrape_000231
231
longxing_Grafting2_ems_3hM_1912_0001_0011_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDIQKDAELVRLKVTLALRMQGDNEKIRTLATKATKLAEEAQKKNDEEILRKAEELLAKIVRNA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5698
0.4191
0.0891
0.7315
0.8675
0.6659
0.281253
0.078451
41.034534
21.026025
0.295096
0.078451
70.764436
3.414153
0.721281
0.078451
0.078451
ok
null
5
0.290568
0.004277
0.286169
0.2961
0.084417
0.007063
0.074703
0.09334
74.292378
0.277278
73.82826
74.587666
0.140823
0.006263
0.130615
0.149321
0.295424
0.09334
74.563583
0.149321
0
litscrape_000232
232
longxing_Grafting2_HHH_eva_0752_0001_0003_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDRELLKRKVELALRLLGVSEEEIKKVLEKLDRIGDEEEIQRVVAELVRKAQQ
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5438
0.4136
0.0852
0.7226
0.8639
0.6741
0.294239
0.074352
43.914915
19.835053
0.337423
0.074352
62.775571
4.045659
0.569427
0.074352
0.074352
ok
null
5
0.289543
0.005582
0.283863
0.298783
0.082692
0.009875
0.071021
0.098684
65.449836
0.431657
64.920277
66.158939
0.130566
0.007023
0.117708
0.138704
0.298783
0.098684
66.158939
0.138704
0
litscrape_000233
233
longxing_Grafting2_ems_3hM_843_0001_0012_0001_0001
Cao et al IL7Ra
IL7Ra
1
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDTKLARRKVKLALTIVKNASSKEEADRALHIAEIVADEVNEPTLQEQVTRTKKWVEKYFS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7043
0.4447
0.0832
0.6912
0.8746
0.6781
0.29563
0.114796
45.258149
19.446301
0.345078
0.114796
74.484421
2.368128
0.771506
0.114796
0.114796
ok
null
5
0.292127
0.00519
0.282849
0.297676
0.103814
0.014759
0.085329
0.126389
75.407511
0.187926
75.201558
75.709354
0.165886
0.01174
0.150424
0.184268
0.297676
0.126389
75.709354
0.184268
0
litscrape_000234
234
bcov_v4_r3_HEEH_15440_000000053_0001_0001_1_21_H____ems_3hM_1700_0001_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DDVRKVAHIAIRLAALAEHDPRKKEDVQRSLKKLVTEAEKKNDEAAIRAVRIILEQVSKKV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.618
0.4432
0.094
0.6881
0.8492
0.5992
0.341093
0.116404
52.242325
17.23913
0.397389
0.116404
69.205418
2.953255
0.736824
0.116404
0.116404
ok
null
5
0.326507
0.017167
0.296996
0.347887
0.138135
0.027617
0.109734
0.181145
72.634021
0.443981
71.807573
73.053027
0.186046
0.028467
0.154495
0.231395
0.333967
0.181145
72.983439
0.231395
0
litscrape_000235
235
IL7Ra_binder_design_67
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEAEALREAAKQVLEFAKKFSEKIPEKYSKKLLELAEKAAEALEKAAEAVEKGDEEEREKWLEERDKYLEEIFDIVDEYLEES
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8061
0.3877
0.1201
0.5961
0.8162
0.4494
0.345323
0.093593
36.01204
21.37526
0.237657
0.093593
74.515547
2.336829
0.843216
0.093593
0.093593
ok
null
5
0.35232
0.001853
0.350035
0.355528
0.113121
0.008723
0.105273
0.129103
75.158619
0.341581
74.736304
75.518493
0.16096
0.006902
0.154781
0.173694
0.352062
0.129103
75.49681
0.173694
0
litscrape_000236
236
longxing_Grafting2_ems_4hC_633_0001_0001_0006_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEAELLSKKLALAAKLGNLTLIKAVLDEARQNKVDEEVTKLAKKLNPQAEELIKRAEKNM
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7214
0.4233
0.0841
0.6955
0.8716
0.6812
0.298455
0.127922
50.315127
18.618999
0.345832
0.127922
73.297424
2.4093
0.775476
0.127922
0.127922
ok
null
5
0.300634
0.004838
0.29289
0.305666
0.127728
0.013568
0.104347
0.143215
75.731923
0.496687
75.077236
76.243215
0.173771
0.010173
0.157866
0.187563
0.305666
0.143215
76.233077
0.187563
0
litscrape_000237
237
longxing_Grafting2_HHH_eva_0253_0002_0007_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEDEATKHARLVLEAAQRGDTKTLRKILEELRRLLEETGDPNVELARMKAKIALDMVK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6246
0.4369
0.1005
0.6838
0.8399
0.6094
0.291903
0.085374
44.625201
19.695756
0.33913
0.085374
68.179582
2.984054
0.705811
0.085374
0.085374
ok
null
5
0.310612
0.012864
0.286915
0.323215
0.095807
0.011321
0.079624
0.114881
71.652393
0.493102
71.030966
72.340469
0.148728
0.012152
0.137614
0.17131
0.317342
0.114881
72.076666
0.17131
0
litscrape_000238
238
longxing_ems_3hM_3682_000000004_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEDLLQDALLILLRLIAQVKDPKVEKLAQEIAETALELNKKVSSDEAAKIVEKLVKEVEKQAK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4463
0.3927
0.0858
0.7424
0.8638
0.6657
0.287346
0.068548
41.685322
20.285466
0.336199
0.068548
53.168086
7.788973
0.43305
0.068548
0.068548
ok
null
5
0.272464
0.010553
0.252281
0.282
0.059899
0.007551
0.049692
0.071455
55.028422
0.171745
54.813375
55.303061
0.112568
0.00989
0.10234
0.129772
0.275146
0.071455
55.303061
0.129772
0
litscrape_000239
239
longxing_Grafting2_ems_3hC_242_0001_0002_0006_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEDTRLAELKVRQAATIAKNAGDPNEAERALEIAEIVAQQANDPRLEKLVKKLSEEVRKTV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6336
0.4428
0.0914
0.6821
0.8511
0.6159
0.295529
0.081933
43.950196
19.659662
0.345505
0.081933
68.606654
2.924984
0.707157
0.081933
0.081933
ok
null
5
0.284911
0.012026
0.268684
0.303905
0.077876
0.010017
0.061974
0.09008
71.746169
0.30109
71.181863
72.016291
0.135031
0.015611
0.115127
0.149832
0.287218
0.085958
72.016291
0.149832
0
litscrape_000240
240
longxing_ems_3hC_740_0001_000000001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEDTSRTAKDLLKKAKEAVERNDSETVKKLLQKVIRIAVRAGDDEVSKAVADLMMLAAKIS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5062
0.4077
0.091
0.7226
0.8608
0.6475
0.283656
0.07877
42.099535
20.160442
0.330729
0.07877
65.646573
3.981064
0.59636
0.07877
0.07877
ok
null
5
0.279444
0.004139
0.274121
0.286281
0.111897
0.011063
0.095438
0.125296
69.061912
0.368886
68.707095
69.53198
0.15958
0.011197
0.144954
0.177178
0.286281
0.125296
69.53198
0.177178
0
litscrape_000241
241
longxing_Grafting2_ems_3hC_859_0001_0005_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEEEEIRTMLKILKDQASNASSDEERKLNKRKVNIMARQIPDPTARKVAKEINETLNKLE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4567
0.427
0.086
0.7591
0.8674
0.661
0.304237
0.072379
45.709133
19.214017
0.356926
0.072379
48.381128
13.502967
0.319907
0.072379
0.072379
ok
null
5
0.295155
0.006943
0.287312
0.307407
0.069326
0.01555
0.041366
0.08172
54.096666
1.83351
50.548695
55.784182
0.130302
0.012285
0.109212
0.141691
0.307407
0.063207
50.548695
0.141691
0
litscrape_000242
242
longxing_Grafting2_ems_3hM_1581_0002_0013_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEEETDQKLLERKLRMAAKLAKDDPDAAEVIIDAIYMQAKDLGDEKILRLAEKAKRIVQKIK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6618
0.4358
0.0831
0.7043
0.8745
0.6271
0.284557
0.09653
41.488096
20.494875
0.31917
0.09653
71.328824
3.184435
0.740698
0.09653
0.09653
ok
null
5
0.281963
0.005862
0.273058
0.287937
0.080158
0.008137
0.067577
0.088734
72.218689
0.216691
71.855713
72.496511
0.139735
0.010552
0.124359
0.152069
0.286669
0.086556
72.496511
0.152069
0
litscrape_000243
243
bcov_r3_HEEH_10171_000000024_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEETHKTAQKLYQTVWRLSKKGKPYELRIDNDGTTIRIEIDSDPRVADEVLTRLYEILARLLRK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.417
0.4347
0.0775
0.7713
0.9038
0.758
0.286109
0.07352
43.993877
19.99402
0.337351
0.07352
48.986532
9.635865
0.401105
0.07352
0.07352
ok
null
5
0.3
0.005666
0.293399
0.310207
0.064101
0.011183
0.050142
0.077869
48.480898
0.487623
47.78499
48.936884
0.125677
0.008553
0.115119
0.136009
0.310207
0.077869
48.936884
0.136009
0
litscrape_000244
244
bcov_r3_HEEH_02947_000000071_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEFSKKAKKLFQELLETAEKQGTILLLTLEVNGIEYFVSVSSDPEDQRLARIRVKWIIEYAQKR
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5332
0.4204
0.1033
0.6936
0.8384
0.5563
0.304144
0.091479
43.154092
19.910249
0.354401
0.091479
60.394142
4.52883
0.618896
0.091479
0.091479
ok
null
5
0.298905
0.007845
0.286103
0.310883
0.094441
0.009743
0.077392
0.104387
62.015792
0.704863
61.043658
63.150429
0.152844
0.005945
0.144621
0.159708
0.310883
0.100028
61.767544
0.159708
0
litscrape_000245
245
bcov_v4_r2_HEEH_19357_000000010_0001_0001_44_64_H____ems_3hM_250_0001_0002_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEHARKIIEITLHLAKEDARDPRIQKKIDKVLTKFKEAVKKNDEDKLKEVARQAAKLALQALD
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6422
0.3875
0.0946
0.6729
0.8412
0.5839
0.28042
0.080979
42.017658
20.348371
0.321463
0.080979
71.354782
2.725769
0.725163
0.080979
0.080979
ok
null
5
0.287158
0.007455
0.277799
0.297136
0.087017
0.010891
0.07354
0.10146
72.571217
0.128558
72.400941
72.7343
0.141889
0.012316
0.124157
0.15622
0.297136
0.10146
72.468318
0.15622
0
litscrape_000246
246
bcov_v3_r2_HEEH_10005_000000033_0001_0001_1_21_H____HEEH_05755_0001_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEIEKKLERLVTALLRLAQEIGYPVVFDLDFNGEKYRVEIPPNPEEAKQVLREARKIWKEAQTK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6291
0.4257
0.1269
0.6512
0.812
0.5521
0.332126
0.26988
43.73163
19.888667
0.334984
0.26988
67.321885
3.417079
0.670131
0.26988
0.26988
ok
null
5
0.345956
0.001785
0.344344
0.349407
0.364331
0.00831
0.354871
0.378447
69.111871
0.155697
68.88102
69.350066
0.375442
0.007206
0.36833
0.388203
0.349407
0.378447
69.350066
0.388203
0
litscrape_000247
247
longxing_Grafting2_ems_3hM_1272_0001_0009_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEKDLELLLRKVKIAAKLKNNEEYAKKVEKTVEKIEKSIPDPTEATKVATEFLQDVVIQLVV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.631
0.4057
0.0749
0.7254
0.891
0.726
0.295531
0.067444
51.3705
18.527278
0.349228
0.067444
62.049481
6.171795
0.594667
0.067444
0.067444
ok
null
5
0.305151
0.024438
0.286149
0.349645
0.091054
0.012795
0.066338
0.101864
65.49078
0.46244
64.886745
66.054373
0.143677
0.014152
0.116555
0.154359
0.313558
0.0925
65.748128
0.154359
0
litscrape_000248
248
IL7Ra_binder_design_27
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEKEKMLKEAEKLISAITGIKVEVRIEGDEVVIKLEKATEESKALAEDTAEKLATYFGLKAKVEA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7344
0.4014
0.0944
0.6697
0.854
0.6034
0.296726
0.083607
42.895802
20.432514
0.326445
0.083607
73.425876
2.546388
0.78533
0.083607
0.083607
ok
null
5
0.304972
0.00916
0.288732
0.314396
0.09443
0.013271
0.070177
0.108985
75.251732
0.260762
74.891897
75.670164
0.150492
0.013838
0.125516
0.165571
0.314396
0.108985
75.670164
0.165571
0
litscrape_000249
249
IL7Ra_binder_design_90
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEKKEQAQKLFEGIIENRDDAEFVRKAALEIAELFPLAAEEIREAAEKFREAAEALKEDKEKGEELFKEAVELLRDALVKGFELEAEKEKK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7476
0.4105
0.0885
0.6542
0.8882
0.6806
0.340205
0.098763
37.48671
21.962549
0.26343
0.098763
73.670672
3.417102
0.755665
0.098763
0.098763
ok
null
5
0.341421
0.005809
0.331661
0.348965
0.088653
0.012654
0.071506
0.110491
73.945117
0.599399
73.007733
74.877356
0.145897
0.008146
0.1341
0.158186
0.348965
0.110491
74.877356
0.158186
0
litscrape_000250
250
bcov_v3_r3_EHEE_04948_000000023_0001_0001_15_38_H____EHEE_07010_0001_0002_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DESFTLEFEIRGYSPEQAKKLVDYLKRRLKKTADELRKNGLDVKVSVSYSNTGDSVTVKLKITTR
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6418
0.4134
0.0828
0.7016
0.8822
0.6125
0.308546
0.077001
45.706563
19.066989
0.367901
0.077001
65.243352
3.503842
0.668951
0.077001
0.077001
ok
null
5
0.308702
0.010113
0.295437
0.325323
0.11911
0.037164
0.057658
0.149245
66.192768
0.504447
65.264499
66.602111
0.172144
0.031133
0.121987
0.20056
0.308919
0.149245
66.046047
0.20056
0
litscrape_000251
251
longxing_ems_3hC_836_0002_000000016_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DESQKETLTKLIKLAVKAIMNNDPDTAKKVVDKLRKVASEANDHMAKLVADLLEDMVRELK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7459
0.4045
0.0916
0.6752
0.8572
0.5736
0.282749
0.076042
40.579348
21.001106
0.296851
0.076042
73.180468
2.383235
0.793348
0.076042
0.076042
ok
null
5
0.290377
0.004211
0.285127
0.295059
0.086176
0.006405
0.07804
0.095741
74.658895
0.324602
74.363058
75.285439
0.139221
0.00876
0.1293
0.151353
0.295059
0.095741
74.628881
0.151353
0
litscrape_000252
252
bcov_r3_HEEH_16868_000000008_0001_0001
Cao et al IL7Ra
IL7Ra
1
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DETAELILKLASIALTVLAEVNDKVTVDITFNGYTVRVDLDRDPKKAQEAIRRALEYLEKANKK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4683
0.4043
0.0811
0.7412
0.8721
0.6569
0.284297
0.07224
43.409895
19.799352
0.333687
0.07224
54.62066
8.259887
0.553379
0.07224
0.07224
ok
null
5
0.278398
0.01384
0.265236
0.304033
0.060981
0.003585
0.057655
0.066719
55.615621
0.10747
55.531254
55.82773
0.121196
0.003593
0.1171
0.126265
0.267173
0.066719
55.584581
0.126265
0
litscrape_000253
253
bcov_r3_ems_3hC_1630_000000079_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEVEKIAKTLLEKAAKALRNNDKDKVETALREVEDLKKKAQDPKLRELLDVVYILVKLALTM
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6273
0.3939
0.0878
0.6994
0.869
0.6275
0.276976
0.08793
42.707791
20.147091
0.322741
0.08793
66.919555
3.41961
0.653943
0.08793
0.08793
ok
null
5
0.281205
0.009414
0.26327
0.290756
0.10882
0.02376
0.062526
0.129977
68.905491
1.038226
67.228573
70.482944
0.143689
0.020123
0.104635
0.162133
0.290756
0.129977
70.482944
0.162133
0
litscrape_000254
254
bcov_r4_EHEE_rd4_0066_min_rise1_31_000000005_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEVFLVHGEEIAREIMEKAKRQNLRVYIVIRNGIFFVVIW
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4244
0.4445
0.1066
0.735
0.8362
0.6611
0.28856
0.087879
42.458263
20.579485
0.315719
0.087879
42.651542
6.979067
0.342405
0.087879
0.087879
ok
null
5
0.296687
0.006043
0.289461
0.305795
0.108797
0.034681
0.066187
0.168807
51.58876
1.792834
50.131794
55.084348
0.170839
0.020632
0.148098
0.206566
0.293227
0.168807
55.084348
0.206566
0
litscrape_000255
255
bcov_v4_r4_ems_p1_15H_GBL_16H_GBL_16H_0129_0001_0001_0002_000000002_0001_0001_19_34_H____ems_p1_16H_GBL_16H_GABBL_16H_0045_0001_0001_0002_0001_0001_0001_0001
Cao et al IL7Ra
IL7Ra
1
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DEVHKLAEKAARLALKKGDWDAHAKVVNVFLALKHGIISKEQAKKILKKIIEEILS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7457
0.4301
0.1015
0.6556
0.8236
0.5593
0.285548
0.096957
43.793341
20.003911
0.323997
0.096957
74.503684
1.866234
0.797033
0.096957
0.096957
ok
null
5
0.288416
0.007832
0.27774
0.299445
0.101123
0.02151
0.067781
0.131967
74.899883
0.427385
74.292102
75.412171
0.151433
0.017728
0.125837
0.181527
0.299445
0.131967
75.412171
0.181527
0
litscrape_000256
256
IL7Ra_binder_design_43
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DFDDVQAAAVEGVKLVRETAAADKDPEAIAKAAKEAAEKLKKKAPEVADLYEKAVEEATALAKAGDIEGAVKAFEDHVAEALRKYAA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8433
0.4076
0.0952
0.6327
0.8782
0.5894
0.344736
0.072935
39.026615
21.644449
0.278833
0.072935
82.543447
2.061157
0.866819
0.072935
0.072935
ok
null
5
0.351967
0.004999
0.342726
0.357826
0.089412
0.011859
0.069009
0.105967
82.918114
0.260795
82.618412
83.276316
0.16228
0.009396
0.145181
0.173316
0.353423
0.105967
83.276316
0.173316
0
litscrape_000257
257
longxing_Grafting2_ems_p1_15H_GBL_16H_GABBL_16H_0381_0001_0001_0002_0001_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DHRKIIKKAEKLAKKKGDRLAERKVDQARKLADNGKLSPRAASLLAKAIIAQLNQ
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7188
0.4389
0.0855
0.6975
0.8676
0.6944
0.327464
0.150311
51.628163
17.71658
0.373974
0.150311
75.52179
1.936431
0.778716
0.150311
0.150311
ok
null
5
0.340718
0.014045
0.320343
0.357502
0.177902
0.027135
0.133824
0.219472
77.343528
0.753941
76.061082
78.257723
0.221352
0.014778
0.200737
0.245875
0.351487
0.219472
77.903049
0.245875
0
litscrape_000258
258
longxing_ems_3hM_1317_000000043_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DKEELKKKIHKLAQIVARHHREDDSTVNDVAVIVLKLLRQDTEEALKKAVELVKTLASKANS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5571
0.4402
0.0812
0.7312
0.8781
0.6615
0.255969
0.08009
39.805515
21.1377
0.294741
0.08009
61.525992
6.468039
0.585245
0.08009
0.08009
ok
null
5
0.252193
0.004238
0.245239
0.258364
0.077332
0.005776
0.066398
0.08355
62.681566
0.320766
62.215612
62.967359
0.119755
0.006039
0.108048
0.124814
0.251183
0.078516
62.92438
0.124814
0
litscrape_000259
259
bcov_v3_r3_HEEH_04578_000000011_0001_0001_44_64_H____ems_3hM_2978_0001_0002_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DKKELSDTAEKLLKDALDKNDEDKFVEALLYAAKVAKDVNDERLLRIVQKLAREFIRRLM
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7281
0.3862
0.0887
0.6776
0.8552
0.6527
0.273451
0.063262
44.003364
20.571085
0.32059
0.063262
73.339741
2.341383
0.784505
0.063262
0.063262
ok
null
5
0.279741
0.011759
0.261677
0.297009
0.087012
0.032825
0.053862
0.149028
75.551359
0.467204
75.038004
76.370292
0.138206
0.026451
0.115188
0.188506
0.297009
0.149028
76.370292
0.188506
0
litscrape_000260
260
longxing_Grafting2_ems_3hC_836_0001_0010_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DKLQKMKLELAERIARKLLKDNDPDSAKRAVHQLRIVADEANDEEAKKIADELEKQVRKLK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.731
0.4439
0.1082
0.6484
0.8195
0.5453
0.303091
0.118837
42.90295
19.696782
0.338597
0.118837
73.282875
2.367764
0.774021
0.118837
0.118837
ok
null
5
0.299731
0.008582
0.28352
0.308171
0.110561
0.017564
0.078497
0.128376
73.569865
0.404732
72.98205
74.253149
0.172017
0.014071
0.145092
0.184811
0.308171
0.124444
74.253149
0.184811
0
litscrape_000261
261
bcov_v4_r4_ems_p1_15H_GBL_16H_GBL_16H_0129_0001_0001_0002_000000002_0001_0001_19_34_H____ems_p1_15H_GABBL_14H_GBL_16H_0666_0001_0001_0002_0001_0001_0001
Cao et al IL7Ra
IL7Ra
1
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DKRKKLEKIAERLAREGKLDEEEAEKLAREAWKAGDEELLAKIVNAWLHAKLS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5547
0.4231
0.1002
0.7029
0.8335
0.567
0.304751
0.075983
47.260351
18.950004
0.350173
0.075983
63.718497
3.554468
0.655711
0.075983
0.075983
ok
null
5
0.290477
0.018132
0.268514
0.319966
0.088761
0.007572
0.074349
0.09646
65.136289
0.583785
64.396296
66.028189
0.141706
0.015289
0.11844
0.162072
0.319966
0.08957
64.950696
0.162072
0
litscrape_000262
262
longxing_ems_3hC_1281_000000006_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DLDEKITTLYKELVKVVMNAKDEEQAKLALEAAATILVQAATSDEKTKEEVSKLAEKLVKTASS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5075
0.4015
0.076
0.7402
0.89
0.7078
0.298715
0.064691
43.455592
19.681971
0.355397
0.064691
60.213906
5.311807
0.529215
0.064691
0.064691
ok
null
5
0.27737
0.005433
0.272836
0.286485
0.069433
0.00759
0.06068
0.0819
62.523666
0.158024
62.282152
62.752099
0.125028
0.005711
0.120247
0.134703
0.280798
0.068996
62.282152
0.134703
0
litscrape_000263
263
bcov_v3_r2_ems_3hM_634_000000018_0001_0001_45_64_H____ems_3hM_1055_0001_0002_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DLSKKIKTLIDLIKKIAKSKDDEYLKLLAKALERAMKDASKKNDEEWLRDVLYSAEAVLRHC
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7734
0.4235
0.1095
0.6437
0.826
0.4629
0.313926
0.113462
40.847159
20.924818
0.302957
0.113462
74.067917
1.911187
0.817828
0.113462
0.113462
ok
null
5
0.30956
0.004399
0.300963
0.312804
0.107612
0.006027
0.095895
0.112281
73.970824
0.334386
73.382858
74.286904
0.165649
0.007696
0.150634
0.171993
0.312804
0.112281
74.286904
0.171993
0
litscrape_000264
264
longxing_ems_3hM_2137_000000003_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DMVEISVEALSDHAEKAVKSGDEETAKILISVLEAILKRTPENPASELVKTVVTKLKQLLKS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5692
0.4003
0.0847
0.7087
0.8633
0.636
0.317948
0.067587
47.783203
18.947562
0.377417
0.067587
65.720161
4.612819
0.669744
0.067587
0.067587
ok
null
5
0.2949
0.010628
0.284417
0.315269
0.077125
0.007294
0.067956
0.089607
68.094416
0.374463
67.655614
68.654618
0.141856
0.008406
0.128166
0.154347
0.315269
0.089607
68.654618
0.154347
0
litscrape_000265
265
longxing_ems_p1_15H_GBL_16H_GBL_14H_0057_0001_0001_0002_000000006_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DPIDVAQKATHLLITTGDPTFEKIARKIAKAAQKGDKKLADKLRKLLDKAE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6271
0.4315
0.1018
0.6776
0.8193
0.5385
0.282026
0.074948
41.990227
20.391623
0.321404
0.074948
67.431239
3.156527
0.631033
0.074948
0.074948
ok
null
5
0.276765
0.005194
0.268236
0.283533
0.082252
0.008127
0.073351
0.097325
68.151255
0.88284
67.14063
69.76262
0.133859
0.003606
0.129982
0.138497
0.283533
0.081746
67.628183
0.138497
0
litscrape_000266
266
longxing_HEEH_05243_000000005_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DPTARELIRQAADLVIKARKRNTEVDITIDVNGIKVKVRFTTDPKDQDKALELIQDAIVLSVAG
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4523
0.4271
0.0726
0.7565
0.9037
0.7212
0.279892
0.078297
43.384419
20.409084
0.327255
0.078297
56.728977
6.611815
0.499553
0.078297
0.078297
ok
null
5
0.282862
0.006682
0.274201
0.293531
0.07667
0.020387
0.045227
0.098261
58.652434
0.993573
56.944308
59.670295
0.137753
0.017511
0.108441
0.158948
0.293531
0.093688
59.60922
0.158948
0
litscrape_000267
267
longxing_HHH_eva_0656_000000002_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DPTEHLRRLADQLKDAGVRSKEQIERLLKKAAKELGVSEEEIRRVQEEIRKILN
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.505
0.4399
0.0758
0.7558
0.8865
0.7128
0.309752
0.068222
44.718171
19.728341
0.357972
0.068222
60.104998
4.877966
0.531004
0.068222
0.068222
ok
null
5
0.295314
0.014551
0.271928
0.312171
0.069991
0.011638
0.054654
0.081608
60.220602
0.367637
59.890384
60.908859
0.135299
0.014795
0.112299
0.15342
0.309086
0.081608
60.078807
0.15342
0
litscrape_000268
268
longxing_ems_3hM_2159_000000000_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DQHRVQAELALRLREARKERDPKKVEEILREAQEIAKKLNNPEVLKHVEMFARVVKKLAR
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4972
0.4482
0.1034
0.7215
0.8504
0.6023
0.339508
0.103975
49.926934
17.337766
0.396377
0.103975
57.588533
4.981368
0.510835
0.103975
0.103975
ok
null
5
0.291608
0.01099
0.275106
0.306009
0.091899
0.025904
0.058975
0.134045
59.209064
0.687687
58.341221
60.358786
0.14528
0.022337
0.117768
0.186224
0.306009
0.134045
60.358786
0.186224
0
litscrape_000269
269
longxing_ems_3hM_1894_000000008_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DREEIVKLLKDIANEVASKAKTEKSEELKKWVKKLEDALKKGDRTDHTEAMQSVVQLIIDIK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5513
0.4136
0.0801
0.7356
0.8801
0.6822
0.288333
0.065752
44.854222
19.950583
0.340612
0.065752
63.257591
6.134446
0.624219
0.065752
0.065752
ok
null
5
0.263674
0.006467
0.253032
0.271812
0.065781
0.006298
0.057553
0.073712
64.590298
0.425956
63.951029
65.060359
0.11987
0.006598
0.11276
0.128049
0.271812
0.0725
64.678548
0.128049
0
litscrape_000270
270
bcov_r2_ems_bGC_164_000000018_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DVDLIVRSRDHDIEVRVKDYRQAEKIAKEIAKKLNASVRILVSTNKWVVVVVM
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5637
0.4445
0.0815
0.7247
0.8691
0.6657
0.279366
0.08283
42.197559
20.39246
0.319708
0.08283
52.836618
6.747931
0.531963
0.08283
0.08283
ok
null
5
0.28783
0.012338
0.269029
0.304152
0.081566
0.009706
0.064732
0.095086
52.654753
0.829848
51.111412
53.524461
0.147209
0.010415
0.132126
0.163958
0.297169
0.095086
53.524461
0.163958
0
litscrape_000271
271
bcov_v3_r3_ems_3hM_2959_000000093_0001_0001_24_42_H____ems_3hM_1593_0001_0007_0001_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DVTTVAQKVFRILWELIENAEDERIKELLQRVLALVVNAWRNNDEKLVRDLYKTLEKLVRELRS
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6438
0.4172
0.0771
0.7019
0.8872
0.7359
0.280528
0.068834
46.396743
19.646209
0.331011
0.068834
69.190614
2.89057
0.702575
0.068834
0.068834
ok
null
5
0.287573
0.007458
0.279665
0.298856
0.072403
0.009318
0.06275
0.08911
71.458423
0.317714
71.009182
71.830488
0.133725
0.007401
0.123783
0.145512
0.293299
0.08911
71.830488
0.145512
0
litscrape_000272
272
longxing_Grafting2_HHH_eva_0506_0001_0008_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
DYREVLKKAEKLARKKGDKLAVMKVELALRMADSGKVDPRAAELIARALERMLRT
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5829
0.4407
0.0988
0.6968
0.844
0.6277
0.33919
0.111614
48.970078
18.008386
0.392025
0.111614
65.451904
3.599474
0.622915
0.111614
0.111614
ok
null
5
0.296459
0.011126
0.2809
0.313305
0.091895
0.015759
0.070248
0.107353
65.117015
0.360928
64.676015
65.555451
0.146114
0.011046
0.132973
0.158267
0.291405
0.104821
64.729628
0.158267
0
litscrape_000273
273
IL7Ra_binder_design_56
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EAREEAERLAREAAELVEKDGASKEVAEAIERAILEIFEEKDPEAQETLLEIVKDILETDKKVSEEVKEKVIEAAERARELAEKR
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8218
0.3911
0.1225
0.5944
0.8213
0.4862
0.367828
0.117353
48.604325
18.186987
0.373623
0.117353
77.115953
2.356952
0.847033
0.117353
0.117353
ok
null
5
0.378123
0.00199
0.376243
0.380721
0.16363
0.019052
0.133767
0.186164
78.356926
0.305372
77.954061
78.79604
0.213003
0.018305
0.185859
0.234068
0.380721
0.186164
78.79604
0.234068
0
litscrape_000274
274
IL7Ra_binder_design_51
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEAKKLAKEAIEKIKKTKDPKKAAEIAKETVKKLLAAGAEEEADEVLLAALEKV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7464
0.4173
0.1058
0.6675
0.8291
0.5194
0.294067
0.114616
38.667974
21.274944
0.285837
0.114616
76.01311
2.088257
0.770162
0.114616
0.114616
ok
null
5
0.276913
0.006979
0.267378
0.288396
0.092009
0.008809
0.079424
0.106343
75.939761
0.516093
75.169894
76.562281
0.136682
0.008324
0.124595
0.147077
0.27881
0.093901
75.876637
0.147077
0
litscrape_000275
275
IL7Ra_binder_design_69
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEAKKLVKEAEKKAKEAAEEVVKAAKEGKEAFEKALKKAEKIFSEIREKALKNKEARKEIAEILKKAVEEIFEAVSDEYAK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7565
0.3963
0.1105
0.6328
0.8428
0.5255
0.364813
0.137387
46.4513
18.929387
0.343249
0.137387
75.759277
2.905029
0.803142
0.137387
0.137387
ok
null
5
0.348877
0.010279
0.328412
0.355358
0.111706
0.015792
0.080452
0.123599
74.847638
0.337696
74.315058
75.297884
0.176293
0.013406
0.150117
0.186292
0.354727
0.119092
74.643881
0.186292
0
litscrape_000276
276
longxing_HEEH_05274_000000000_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEDALEAAATVLMTQQRAQKQGQPHTIKHKVRGKDVTVRVGSDPRLQKEAKKVYQEVARVAIRG
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5706
0.4165
0.0806
0.7135
0.8761
0.6746
0.296184
0.070383
45.817652
19.736271
0.351316
0.070383
51.630542
9.120198
0.468397
0.070383
0.070383
ok
null
5
0.328341
0.009558
0.317803
0.344081
0.08193
0.012661
0.064023
0.099072
54.139794
0.810979
52.715695
55.077122
0.145609
0.010056
0.131373
0.157802
0.344081
0.099072
54.373583
0.157802
0
litscrape_000277
277
IL7Ra_binder_design_46
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEEKKEKIEELKKKAEEVAELVEKGDLEGAQKLISEFSVEEAEGIQLYVVAKQLEKKGYKEEAEEQYKEADEVLEKAVE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7788
0.395
0.1115
0.6216
0.8407
0.4857
0.342258
0.100501
47.998939
18.427805
0.335406
0.100501
74.657017
2.334306
0.826892
0.100501
0.100501
ok
null
5
0.360351
0.00723
0.3465
0.367659
0.13218
0.015495
0.106332
0.155087
75.904546
0.538348
74.906497
76.463642
0.187373
0.017363
0.158042
0.212308
0.367659
0.155087
76.463642
0.212308
0
litscrape_000278
278
IL7Ra_binder_design_50
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEEKRREELVEEVRKAAEKAIEIAKKDPSKAHDAYAELVLLARKAVQEEPGIEKAAAELVKEVQKVIDSL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7747
0.42
0.1075
0.6371
0.8376
0.5237
0.315628
0.088426
40.829371
20.674902
0.314802
0.088426
76.314637
2.082212
0.824081
0.088426
0.088426
ok
null
5
0.32221
0.006635
0.310626
0.329964
0.104169
0.014381
0.081676
0.126874
77.212831
0.289796
76.904659
77.606879
0.166408
0.010171
0.15028
0.1808
0.329964
0.126874
77.492832
0.1808
0
litscrape_000279
279
IL7Ra_binder_design_91
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEERLKKALEEAEKAYEELKKAADELGKKIDEKEAESIKKAAEVALEYAKKGNAEEAERAKYILKSRKEEVEDEVKK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6952
0.4046
0.1075
0.6477
0.8431
0.4855
0.335283
0.10657
41.330956
20.166016
0.294458
0.10657
74.91387
2.573458
0.799483
0.10657
0.10657
ok
null
5
0.336972
0.003015
0.33147
0.33947
0.106462
0.003468
0.100113
0.109165
75.35312
0.287639
74.992581
75.732495
0.164416
0.008195
0.148237
0.169858
0.338554
0.109165
74.992581
0.169858
0
litscrape_000280
280
IL7Ra_binder_design_19
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEKDKYIEEAQYVAVEALEYIKDGTAEEGEKAKEEAEKKIRELLTKAGVSEEQIEEAVELFNKEANKLIEEVKK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8124
0.4037
0.0995
0.6417
0.8562
0.496
0.325182
0.091255
35.706344
22.076688
0.259473
0.091255
75.690868
2.343069
0.826503
0.091255
0.091255
ok
null
5
0.326339
0.004935
0.319358
0.332948
0.097727
0.008744
0.081617
0.106556
75.918582
0.456354
75.331875
76.391443
0.155435
0.007996
0.140401
0.16238
0.332948
0.101012
76.31559
0.16238
0
litscrape_000281
281
IL7Ra_binder_design_94
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EEKIKKAKEYRKKAIEALKAGDIDKFDELLAKFIEYAYESGKFEEFEKEFLKEYEK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.6946
0.418
0.0995
0.6796
0.8406
0.4984
0.278797
0.088533
41.685355
20.361732
0.319641
0.088533
67.620315
3.584738
0.706219
0.088533
0.088533
ok
null
5
0.273373
0.006344
0.264676
0.282324
0.095611
0.011196
0.079022
0.108611
67.386017
0.555525
66.582095
67.908902
0.146826
0.010133
0.128201
0.158747
0.278738
0.101139
67.770887
0.158747
0
litscrape_000282
282
IL7Ra_binder_design_85
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EELEKLLEELGKKLRRAVELAAEGGPEEEIRKELEEAGELYIKATLLSPEGAEAARILVEMAIDALELANPKAAEIARKLFEEAEEKAKKL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8453
0.4395
0.1911
0.514
0.7225
0.3876
0.412644
0.176444
39.635243
21.035434
0.296811
0.176444
81.049012
2.057677
0.865243
0.176444
0.176444
ok
null
5
0.404657
0.00345
0.401504
0.411027
0.168519
0.012382
0.156045
0.191657
80.789927
0.238554
80.525934
81.219267
0.227718
0.013665
0.208725
0.247855
0.411027
0.191657
81.219267
0.247855
0
litscrape_000283
283
IL7Ra_binder_design_47
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EENLEKAQEELAKAIALGRKLGEKADEKLADEYVAEIQLLFRKAVEYKKKGDLEKAKKEVDEALELVKKFVEEVEKKTGEDGSEVLEHIEKAAKLLKE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7217
0.3908
0.0885
0.6487
0.8894
0.6692
0.357694
0.089033
51.172575
18.401075
0.361793
0.089033
77.094838
3.29213
0.789506
0.089033
0.089033
ok
null
5
0.365584
0.001695
0.362548
0.367161
0.095486
0.00191
0.093467
0.098911
77.887921
0.350767
77.484375
78.484401
0.166344
0.007297
0.156828
0.173975
0.362548
0.098911
77.586912
0.173975
0
litscrape_000284
284
IL7Ra_binder_design_42
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EIEELIKKAAELLQKGKYEEAKELAEKAKEEAKKKGDEELAVKAEIVADLA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7691
0.4087
0.1036
0.6714
0.8327
0.5141
0.268291
0.090466
44.81512
19.880012
0.298778
0.090466
75.00973
1.757617
0.793856
0.090466
0.090466
ok
null
5
0.282685
0.005574
0.27498
0.290582
0.108939
0.006897
0.098499
0.117606
75.61348
0.155724
75.417121
75.827515
0.145737
0.008602
0.133795
0.158348
0.290582
0.117606
75.617718
0.158348
0
litscrape_000285
285
IL7Ra_binder_design_38
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EKEEEKIKIKKEVQELIEEAVQASAEAKDKEKAKKLLEEARKLAEKAIKAAEEDIEKAKEYLEKVKKLKEEIKKLAEE
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8573
0.4003
0.0871
0.6644
0.8969
0.6551
0.321548
0.071608
41.639361
21.179818
0.295088
0.071608
78.96542
2.362286
0.835508
0.071608
0.071608
ok
null
5
0.338669
0.006301
0.329576
0.347296
0.097819
0.011289
0.08268
0.114493
79.759679
0.703659
79.041985
80.836832
0.15669
0.007318
0.14682
0.168434
0.347296
0.114493
80.31043
0.168434
0
litscrape_000286
286
IL7Ra_binder_design_63
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EKELEEAKKALEKAVELVKKAADEELAKEIEEKVEEAKKALEEDPEKAIKIAEEAAKKVAEYIIENKDLSEEDKEALVEAVDHLQEAIALAAIKEAKKK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8164
0.3888
0.1198
0.5893
0.8391
0.4951
0.389036
0.108473
34.158205
22.246151
0.243866
0.108473
78.466111
2.51598
0.860787
0.108473
0.108473
ok
null
5
0.392667
0.001443
0.390373
0.394875
0.115884
0.008268
0.108452
0.131595
79.095922
0.248031
78.837981
79.519682
0.173296
0.005575
0.167095
0.183814
0.392689
0.131595
79.519682
0.183814
0
litscrape_000287
287
IL7Ra_binder_design_49
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EKIEKIAEALREAMLEVGEETGYKEEAEKEAEKAAEILKEDFAEGVLYAGRAAKEIGEKGGLSDLEINKRIQEMREKAEEIYDG
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8162
0.4057
0.1129
0.6103
0.8391
0.5148
0.347671
0.092262
39.566024
21.427039
0.286177
0.092262
79.065915
2.162661
0.841049
0.092262
0.092262
ok
null
5
0.350283
0.001442
0.348703
0.352819
0.096022
0.002276
0.093174
0.099469
79.763955
0.38834
79.3891
80.451633
0.156622
0.005017
0.150139
0.163076
0.348703
0.096363
79.54863
0.163076
0
litscrape_000288
288
IL7Ra_binder_design_40
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EKKEKLEKIKEELEKKGDYDLAIAVVQIEEYLEEGDEKSAEKLAEQYAKKTGKKELIKEILEIAK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8055
0.4286
0.1093
0.6428
0.8339
0.4854
0.337731
0.15711
39.903807
20.894629
0.301026
0.15711
77.691495
2.134157
0.790407
0.15711
0.15711
ok
null
5
0.3429
0.003063
0.338391
0.347187
0.175785
0.005474
0.167907
0.183842
78.182183
0.326543
77.75789
78.760406
0.225875
0.00774
0.21557
0.235615
0.34521
0.179147
78.194512
0.235615
0
litscrape_000289
289
IL7Ra_binder_design_24
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
EYKERLKRAVESVKKGEDEEEAGKEALELLEEISEEEFAKILQEVVKEEGYDVDVVQELLALLVEAKL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5958
0.406
0.0984
0.6883
0.8539
0.5863
0.273185
0.081814
40.767637
20.733266
0.319925
0.081814
63.460297
5.156283
0.607933
0.081814
0.081814
ok
null
5
0.265153
0.003186
0.260896
0.270659
0.080923
0.003657
0.074016
0.083782
63.972601
0.337102
63.481252
64.400041
0.128497
0.00405
0.120806
0.131308
0.26394
0.083782
64.400041
0.131308
0
litscrape_000290
290
bcov_r3_ems_ferrM_4303_000000002_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
FVIILIHAKDKEYVEIAIKIAQPKLFQVNDNRTVLVVLDDPEKAKKVVELVRKIADVEVLIDT
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7361
0.4122
0.0833
0.6793
0.863
0.6593
0.279571
0.065691
45.242349
20.208455
0.323579
0.065691
74.048389
2.247641
0.782941
0.065691
0.065691
ok
null
5
0.283329
0.003413
0.278128
0.286797
0.067517
0.005996
0.059001
0.074639
74.622851
0.235911
74.316485
74.929202
0.124351
0.00314
0.120841
0.129112
0.285129
0.073018
74.578844
0.129112
0
litscrape_000291
291
bcov_r3_EHEE_10073_000000036_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
GDSHTHTVDVPYTDPNEAKKFLDKVRKELKKLKEEAEKNGRLFWFSVRLVTKNNRFNVFFLWFTM
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.477
0.412
0.0831
0.7301
0.8748
0.5999
0.270058
0.084109
43.318308
20.035944
0.31529
0.084109
47.363638
10.09234
0.490077
0.084109
0.084109
ok
null
5
0.286401
0.005026
0.281518
0.295804
0.077493
0.006708
0.066116
0.087091
49.873005
0.499995
49.201332
50.612854
0.136329
0.004145
0.132793
0.144338
0.295804
0.087091
50.612854
0.144338
0
litscrape_000292
292
IL7Ra_binder_design_34
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
GEEERRRYFFEAAVEKMKDLGAVKVELRGDKLLVTTETEEAKEEARPFAAIAAKALGVEYEVEVA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7484
0.4324
0.0933
0.6637
0.8541
0.5722
0.302324
0.096513
47.423821
19.078693
0.355243
0.096513
74.705384
2.14909
0.809964
0.096513
0.096513
ok
null
5
0.29356
0.004042
0.289555
0.299919
0.076048
0.00841
0.068229
0.089867
74.86861
0.08994
74.736154
74.959066
0.13893
0.010052
0.127998
0.155133
0.299919
0.089867
74.903781
0.155133
0
litscrape_000293
293
bcov_r3_ems_ferrM_5651_0001_000000016_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
GITIFINADDPTVAELAKSANPKHAHFHPAGAVWIELDDPTASKIVEKVAKNANADVVVREA
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4123
0.4653
0.0837
0.7618
0.8849
0.7139
0.304979
0.086826
45.24968
19.434704
0.359153
0.086826
49.210697
9.142203
0.372731
0.086826
0.086826
ok
null
5
0.296435
0.007756
0.28536
0.305435
0.075582
0.010566
0.05691
0.083861
52.012697
0.575388
51.013276
52.684814
0.144066
0.009372
0.126055
0.152876
0.291678
0.083861
52.684814
0.152876
0
litscrape_000294
294
longxing_ems_3hC_151_0002_000000020_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
GPEDVERILKTVLKIARDKNDEQTSATVLILLLQAQELLKDPRKEETAQKLAEMAKKILEKLL
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.5256
0.4108
0.0803
0.7263
0.8746
0.6296
0.26458
0.087227
45.629222
19.724517
0.307058
0.087227
65.762989
3.608166
0.623479
0.087227
0.087227
ok
null
5
0.283049
0.000825
0.281948
0.284317
0.116322
0.003045
0.112255
0.121521
71.292944
0.169044
70.960482
71.422263
0.159824
0.00585
0.154432
0.169318
0.282379
0.121521
71.422263
0.169318
0
litscrape_000295
295
longxing_ems_3hC_703_0001_000000002_0001_0001
Cao et al IL7Ra
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
GREDAAKLFRLVMTAQKRVNDPNLRDQLEEAAALLLQLMRNGVPLDEAVKIASSVVEKVEKSD
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.4577
0.4446
0.0941
0.7288
0.8647
0.6591
0.326123
0.09375
49.243503
17.92455
0.380643
0.09375
60.20046
5.133528
0.544733
0.09375
0.09375
ok
null
5
0.292196
0.013186
0.27618
0.309387
0.09654
0.008087
0.083321
0.105603
62.875996
0.531576
62.047333
63.382259
0.154031
0.010342
0.137518
0.167858
0.289926
0.105603
62.047333
0.167858
0
litscrape_000296
296
bcov_v3_r3_HEEH_04578_000000011_0001_0001_44_64_H____ems_3hC_1310_0001_0001_0013_0001_0001_0001
Cao et al IL7Ra
IL7Ra
1
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
HEVQELARKLWHATEKAEKRNDEKAVKLLEDASVLLVNAWLSNDEDLKKKANKYAKTVIKQAES
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7424
0.4073
0.1025
0.6497
0.8347
0.5068
0.299599
0.088277
36.188866
21.427014
0.248214
0.088277
71.906487
2.087802
0.808717
0.088277
0.088277
ok
null
5
0.306431
0.007007
0.294831
0.313347
0.09765
0.009333
0.082417
0.106994
73.703412
0.345916
73.337603
74.322456
0.14641
0.006233
0.134628
0.152156
0.313347
0.106994
73.454725
0.152156
0
litscrape_000297
297
IL7Ra_binder_design_79
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
HKTLTVEVTKENQEKQLAEAIRKAVKEGATKVIIKYEPDVDEKLLEIAEKQLKDYGIEAEIIPK
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8295
0.4397
0.1067
0.6505
0.8408
0.5543
0.305373
0.11114
39.961952
21.371475
0.283788
0.11114
77.951172
2.052441
0.815829
0.11114
0.11114
ok
null
5
0.300247
0.00481
0.290687
0.303192
0.102432
0.014962
0.073374
0.115919
77.992014
0.235506
77.623295
78.232166
0.15717
0.012721
0.132401
0.168625
0.301629
0.115919
78.066312
0.168625
0
litscrape_000298
298
IL7Ra_binder_design_36
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
HLEEVKKLVIEKAEEFVKEGDIDLAKALLEDAAEVFEEAGHEKEAKELREKAKEV
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.7272
0.4073
0.0925
0.6802
0.8522
0.529
0.273938
0.083518
38.28253
21.579242
0.264583
0.083518
71.122346
1.986929
0.787946
0.083518
0.083518
ok
null
5
0.284602
0.006437
0.278841
0.296955
0.116351
0.027929
0.090128
0.169166
72.044498
0.636387
71.431388
73.16907
0.15363
0.021752
0.131903
0.194724
0.296955
0.169166
73.16907
0.194724
0
litscrape_000299
299
IL7Ra_binder_design_39
RFDiffusion
IL7Ra
0
null
DYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTP
KDEEILKEIEEIKKEIKKKLEEMAKKADDETAKALHVFLATFEKLVEKLIEKGDYEGALEVAREAKEQVEEIEKDPSKVVEATKELQSRLIKLD
ColabDesign AF2-Multimer (model_1_multimer_v3, de novo from sequence, 3 recycles, no MSA)
AF3Score (init_guess on the AF2-predicted complex, no MSA)
0.8432
0.3929
0.0762
0.6454
0.9156
0.7649
0.354172
0.077684
40.817307
21.260303
0.293109
0.077684
78.896842
2.472472
0.849824
0.077684
0.077684
ok
null
5
0.357871
0.004502
0.352274
0.36435
0.078255
0.00686
0.067382
0.086618
80.00204
0.377716
79.626319
80.641058
0.146025
0.010894
0.130841
0.162398
0.352274
0.086618
79.706169
0.162398
0